217503 Cardiotoxin, Naja pallida

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217503-1MG
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      Glass bottle 1 mg
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      Description
      OverviewA cytolytic toxin that causes depolarization of skeletal muscle fibers in vitro. Stimulates Ca2+ transport and ATP hydrolysis by the sarcolemmal Ca2+/Mg2+-ATPase. Its action is strongly potentiated by phospholipase A2. Inhibits protein kinase C (IC50 = 1.8 µM).
      Catalogue Number217503
      Brand Family Calbiochem®
      References
      ReferencesJang, J.Y., et al. 1997. Biochemistry 36, 4635.
      Huang, J.L., and Trumble, W.R. 1991. Toxicon 29, 31.
      Raynor, R.L., et al. 1991. J. Biol. Chem. 266, 2753.
      Grognet, J.M., et al. 1986. Mol. Immunol. 23, 132.
      Product Information
      CAS number11061-96-4
      DeclarationNot available for sale outside of the United States.
      FormLyophilized solid
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥95% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSFH7482450
      Safety Information
      R PhraseR: 20/21/22

      Harmful by inhalation, in contact with skin and if swallowed.
      S PhraseS: 36

      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Cardiotoxin, Naja pallida SDS

      Title

      Safety Data Sheet (SDS) 

      Cardiotoxin, Naja pallida Certificates of Analysis

      TitleLot Number
      217503

      References

      Reference overview
      Jang, J.Y., et al. 1997. Biochemistry 36, 4635.
      Huang, J.L., and Trumble, W.R. 1991. Toxicon 29, 31.
      Raynor, R.L., et al. 1991. J. Biol. Chem. 266, 2753.
      Grognet, J.M., et al. 1986. Mol. Immunol. 23, 132.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision13-June-2016 JSW
      DescriptionA cytolytic toxin that causes depolarization of skeletal muscle fibers in vitro. Stimulates Ca2+ transport and ATP hydrolysis by sarcolemmal Ca2+/Mg2+-ATPase. Its action is strongly potentiated by phospholipase A2. Inhibits protein kinase C (IC50 = 1.8 µM).
      FormLyophilized solid
      CAS number11061-96-4
      RTECSFH7482450
      Purity≥95% by HPLC
      SolubilityH₂O (1 mg/ml)
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Harmful
      Merck USA index14, 1835
      ReferencesJang, J.Y., et al. 1997. Biochemistry 36, 4635.
      Huang, J.L., and Trumble, W.R. 1991. Toxicon 29, 31.
      Raynor, R.L., et al. 1991. J. Biol. Chem. 266, 2753.
      Grognet, J.M., et al. 1986. Mol. Immunol. 23, 132.