208694 Calmodulin, Bovine Brain, High Purity

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208694
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Overview

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208694-1MG
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      208694-5MG
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      Discontinued
      Limited Quantities Available
      Available
        Remaining : Will advise
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          Plastic ampoule 5 mg
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          Description
          OverviewA ubiquitous Ca2+-binding protein that serves as a physiological effector of a wide range of biological processes. Calmodulin highly purified from bovine brain.
          Note: this product cannot be used for animal treatment, in vivo research, or any contact procedure with livestock.
          Catalogue Number208694
          Brand Family Calbiochem®
          SynonymsCaM, Ca2+/Calmodulin
          References
          ReferencesBagchi, I.C., et al. 1992. J. Biol. Chem. 267, 3024.
          O'Neil, K.T., and DeGrado, W.F. 1990. Trends Pharmacol. Sci. 15, 59.
          Harrison, J.K., et al. 1988. J. Neurochem. 51, 345.
          Gopalakrishna, R., and Anderson, W.B. 1983. J. Biol. Chem. 258, 2405.
          Gopalakrishna, R., and Anderson, W.B. 1982. Biochem. Biophys. Res. Commun. 104, 830.
          Sharma, B.K., et al. 1979. Adv. Cyclic Nucleotide Res. 10, 187.
          Product Information
          CAS number73298-54-1
          Unit of DefinitionOne unit is defined as the amount of calmodulin that gives rise to 50% of the maximal enzyme activation of a standard level of activator-deficient calcineurin.
          FormLyophilized
          FormulationLyophilized from 30 mM HEPES, 1 mM CaCl₂, 0.1 mM DTT, pH 7.4.
          Sold on the basis of peptide contentY
          Quality LevelMQ200
          Applications
          Biological Information
          Purity≥95% by SDS-PAGE
          Specific Activity≥250,000 units/mg protein
          Physicochemical Information
          Peptide ContentY
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Dry Ice Only
          Toxicity Standard Handling
          Storage -20°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C or -70°C). Aqueous stock solutions are stable for up to 2 months at -20°C or for up to 4 months at -70°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Calmodulin, Bovine Brain, High Purity SDS

          Title

          Safety Data Sheet (SDS) 

          Calmodulin, Bovine Brain, High Purity Certificates of Analysis

          TitleLot Number
          208694

          References

          Reference overview
          Bagchi, I.C., et al. 1992. J. Biol. Chem. 267, 3024.
          O'Neil, K.T., and DeGrado, W.F. 1990. Trends Pharmacol. Sci. 15, 59.
          Harrison, J.K., et al. 1988. J. Neurochem. 51, 345.
          Gopalakrishna, R., and Anderson, W.B. 1983. J. Biol. Chem. 258, 2405.
          Gopalakrishna, R., and Anderson, W.B. 1982. Biochem. Biophys. Res. Commun. 104, 830.
          Sharma, B.K., et al. 1979. Adv. Cyclic Nucleotide Res. 10, 187.

          Citations

          Title
        • Xinchun Shen, et al. (2005) Scanning the human proteome for calmodulin-binding proteins. Proceedings of the National Academy of Sciences (USA) 102, 5969-5974.
        • Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision26-February-2014 JSW
          SynonymsCaM, Ca2+/Calmodulin
          DescriptionA ubiquitous Ca2+-binding protein distributed in eukaryotic cells that serves as a major physiological effector for a wide range of cellular responses. The Ca2+-calmodulin complex is involved in the maintenance of intracellular Ca2+ homeostasis, as well as in the regulation of the intracellular concentration of other second messengers, such as cyclic AMP and inositol trisphosphate. Calmodulin highly purified from bovine brain.

          Note: This product is not to be used for animal treatment, in vivo research or in any other contact procedure with livestock.
          FormLyophilized
          FormulationLyophilized from 30 mM HEPES, 1 mM CaCl₂, 0.1 mM DTT, pH 7.4.
          CAS number73298-54-1
          Purity≥95% by SDS-PAGE
          Specific activity≥250,000 units/mg protein
          Unit definitionOne unit is defined as the amount of calmodulin that gives rise to 50% of the maximal enzyme activation of a standard level of activator-deficient calcineurin.
          SolubilityAqueous buffers or H₂O. Please refer to the vial label for lot-specific reconstitution volume.
          Storage -20°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C or -70°C). Aqueous stock solutions are stable for up to 2 months at -20°C or for up to 4 months at -70°C.
          Toxicity Standard Handling
          Merck USA index14, 1719
          ReferencesBagchi, I.C., et al. 1992. J. Biol. Chem. 267, 3024.
          O'Neil, K.T., and DeGrado, W.F. 1990. Trends Pharmacol. Sci. 15, 59.
          Harrison, J.K., et al. 1988. J. Neurochem. 51, 345.
          Gopalakrishna, R., and Anderson, W.B. 1983. J. Biol. Chem. 258, 2405.
          Gopalakrishna, R., and Anderson, W.B. 1982. Biochem. Biophys. Res. Commun. 104, 830.
          Sharma, B.K., et al. 1979. Adv. Cyclic Nucleotide Res. 10, 187.
          Citation
        • Xinchun Shen, et al. (2005) Scanning the human proteome for calmodulin-binding proteins. Proceedings of the National Academy of Sciences (USA) 102, 5969-5974.