203702 Brain Derived Neurotrophic Factor, Human, Recombinant, E. coli

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203702
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Overview

Replacement Information

Key Specifications Table

Purity
≥97% by HPLC

Pricing & Availability

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203702-10UG
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      203702-5UG
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          Description
          OverviewRecombinant, human brain drived neurotrophic factor expressed in E. coli. Promotes survival and growth of neurons. Structurally and functionally related to nerve growth factor. Its actions are mediated via the TrkB receptor.
          Catalogue Number203702
          Brand Family Calbiochem®
          SynonymsrhBDNF
          References
          ReferencesErickson, J.T., et al. 1996. J. Neurosci. 16, 5361.
          Leibrock, J., et al. 1989. Nature 341, 149.
          Product Information
          FormLyophilized
          Quality LevelMQ100
          Applications
          Biological Information
          Biological activitySupports survival of rat basal forebrain primary septal cultured neurons. Induces choline acetyltransferase (EC₅₀ = 50 ng/ml)
          Purity≥97% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Protect from Moisture Protect from moisture
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid freeze/thaw cycles of solutions.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Brain Derived Neurotrophic Factor, Human, Recombinant, E. coli SDS

          Title

          Safety Data Sheet (SDS) 

          Brain Derived Neurotrophic Factor, Human, Recombinant, E. coli Certificates of Analysis

          TitleLot Number
          203702

          References

          Reference overview
          Erickson, J.T., et al. 1996. J. Neurosci. 16, 5361.
          Leibrock, J., et al. 1989. Nature 341, 149.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision13-February-2019 JSW
          SynonymsrhBDNF
          DescriptionRecombinant, human brain drived neurotrophic factor expressed in E. coli. Promotes survival and growth of neurons in the central nervous system. Sequence analysis indicates that brain derived neurotrophic factor is structurally and functionally related to nerve growth factor. mRNA for brain derived neurotrophic factor is found predominantly in the central nervous system, whereas mRNA for nerve growth factor is also found in many non-CNS tissues.
          FormLyophilized
          Purity≥97% by HPLC
          Biological activitySupports survival of rat basal forebrain primary septal cultured neurons. Induces choline acetyltransferase (EC₅₀ = 50 ng/ml)
          SolubilityReconstitute to a concentration of ≥10 µg/ml with sterile distilled H₂O or aqueous buffers. For more dilute solutions, add a stabilizing protein such as 0.1% BSA or HSA.
          Storage -20°C
          Protect from moisture
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid freeze/thaw cycles of solutions.
          Toxicity Standard Handling
          Merck USA index14, 6487
          ReferencesErickson, J.T., et al. 1996. J. Neurosci. 16, 5361.
          Leibrock, J., et al. 1989. Nature 341, 149.