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203600 Bohemine

A synthetic, cell-permeable, cyclin-dependent kinase (CDK) inhibitor that is structurally similar to Olomoucine and Roscovitine.

Bohemine MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: [6-Benzylamino-2-(3-hydroxypropylamino)-9-isopropylpurine

Primary Target: CDK
203600
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Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
189232-42-6C₁₈H₂₄N₆O

Pricing & Availability

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203600-1MG
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      		 Plastic ampoule 1 mg
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      Description
      Overview

      This product has been discontinued.





      A synthetic, cell-permeable, cyclin-dependent kinase (CDK) inhibitor (IC50 = 1 µM) that is structurally similar to Olomoucine (Cat. No. 495620) and Roscovitine (Cat. No. 557360). Arrests cell cycle in the G1/S boundary and activates in vitro matured bovine oocytes either alone or in combination with Ionomycin (Cat. Nos. 407950 and 407952).
      Catalogue Number203600
      Brand Family Calbiochem®
      Synonyms[6-Benzylamino-2-(3-hydroxypropylamino)-9-isopropylpurine
      References
      ReferencesChmela, Z., et al. 2001. Drug Metab. Dispos. 29, 326.
      Alberio, R., et al. 2000. Mol. Reprod. Dev. 55, 422.
      Binarova, P., et al. 1998. Plant J. 16, 697.
      Product Information
      CAS number189232-42-6
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₁₈H₂₄N₆O
      Chemical formulaC₁₈H₂₄N₆O
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetCDK
      Primary Target IC<sub>50</sub>1 µM inhibiting cyclin-dependent kinase (CDK)
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Bohemine Certificates of Analysis

      TitleLot Number
      203600

      References

      Reference overview
      Chmela, Z., et al. 2001. Drug Metab. Dispos. 29, 326.
      Alberio, R., et al. 2000. Mol. Reprod. Dev. 55, 422.
      Binarova, P., et al. 1998. Plant J. 16, 697.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision01-August-2010 JSW
      Synonyms[6-Benzylamino-2-(3-hydroxypropylamino)-9-isopropylpurine
      DescriptionA synthetic, cell-permeable, cyclin-dependent kinase (Cdk) inhibitor (IC50 = 1 µM) that is structurally similar to Olomoucine (Cat. No. 495620) and Roscovitine (Cat. No. 495620). Arrests cell cycle in the G1/S boundary and activates matured bovine oocytes either alone or in combination with Ionomycin (Cat. No. 407950 and 407952). Reported to transiently arrest Vicia faba root tip cells at the G1/S and G2/M regulatory points and causes abnormal spindle formation.
      FormWhite solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number189232-42-6
      Chemical formulaC₁₈H₂₄N₆O
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMSO (100 mg/ml) or Methanol (50 mg/ml)
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesChmela, Z., et al. 2001. Drug Metab. Dispos. 29, 326.
      Alberio, R., et al. 2000. Mol. Reprod. Dev. 55, 422.
      Binarova, P., et al. 1998. Plant J. 16, 697.