203408 BLEOCIN™ Antibiotic, Streptomyces verticillus, Cell Culture-Tested - CAS 55658-47-4 - Calbiochem

203408
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Overview

Replacement Information

Key Specifications Table

Empirical FormulaCAS #
C₅₇H₈₉CuN₁₉O₂₁S₂ · 3HCl 55658-47-4

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203408-100MG
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      203408-10MG
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          203408-250MG
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              Description
              OverviewA unique antibiotic of the bleomycin family that is toxic to eukaryotic and prokaryotic cells. BLEOCIN™ Antibiotic cleaves double-stranded DNA and inhibits DNA synthesis, resulting in cell death. Can be used for selection of recombinant clones in a variety of cell types transfected with vectors containing a ble resistance marker. Copper content: ≥3.5%. Potency: ≥750 µg/mg.
              Catalogue Number203408
              Brand Family Calbiochem®
              References
              ReferencesSergeev, D.S., et al. 1995. Bioorg. Khim. 21, 695.
              Mulsant, P., et al. 1988. Somatic Cell and Molecular Genetics 14, 243.
              Ehrenfeld, G.M., et al. 1987. Biochemistry 26, 931.
              Takita, T., et al. 1972. J. Antibiot. 25, 755.
              Product Information
              CAS number55658-47-4
              FormBlue lyophilized solid
              Hill FormulaC₅₇H₈₉CuN₁₉O₂₁S₂ · 3HCl
              Chemical formulaC₅₇H₈₉CuN₁₉O₂₁S₂ · 3HCl
              Hygroscopic Hygroscopic
              Structure formula ImageStructure formula Image
              Quality LevelMQ100
              Applications
              Biological Information
              Purity≥85% by HPLC
              Physicochemical Information
              Dimensions
              Materials Information
              Toxicological Information
              Safety Information according to GHS
              RTECSEC5990700
              Safety Information
              R PhraseR: 20/21/22-36/37/38-40-42/43

              Harmful by inhalation, in contact with skin and if swallowed.
              Irritating to eyes, respiratory system and skin.
              Limited evidence of a carcinogenic effect.
              May cause sensitization by inhalation and skin contact.
              S PhraseS: 22-26-36/37/39-45

              Do not breathe dust.
              In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
              Wear suitable protective clothing, gloves and eye/face protection.
              In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
              Product Usage Statements
              Storage and Shipping Information
              Ship Code Ambient Temperature Only
              Toxicity Harmful & Carcinogenic / Teratogenic
              Storage +2°C to +8°C
              Protect from Light Protect from light
              Hygroscopic Hygroscopic
              Do not freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 year at -20°C.
              Packaging Information
              Transport Information
              Supplemental Information
              Specifications

              Documentation

              BLEOCIN™ Antibiotic, Streptomyces verticillus, Cell Culture-Tested - CAS 55658-47-4 - Calbiochem SDS

              Title

              Safety Data Sheet (SDS) 

              BLEOCIN™ Antibiotic, Streptomyces verticillus, Cell Culture-Tested - CAS 55658-47-4 - Calbiochem Certificates of Analysis

              TitleLot Number
              203408

              References

              Reference overview
              Sergeev, D.S., et al. 1995. Bioorg. Khim. 21, 695.
              Mulsant, P., et al. 1988. Somatic Cell and Molecular Genetics 14, 243.
              Ehrenfeld, G.M., et al. 1987. Biochemistry 26, 931.
              Takita, T., et al. 1972. J. Antibiot. 25, 755.

              Brochure

              Title
              Antibiotics Profiler
              Data Sheet

              Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

              Revision26-September-2007 RFH
              DescriptionA unique antibiotic of the bleomycin family that is toxic to eukaryotic and prokaryotic cells. BLEOCIN™ cleaves double-stranded DNA and inhibits DNA synthesis, resulting in cell death. Can be used for selection of recombinant clones in a variety of cell types transfected with vectors containing a ble resistance marker. Copper content: ≥3.5%. Potency: ≥750 µg/mg.
              FormBlue lyophilized solid
              CAS number55658-47-4
              RTECSEC5990700
              Chemical formulaC₅₇H₈₉CuN₁₉O₂₁S₂ · 3HCl
              Structure formulaStructure formula
              Purity≥85% by HPLC
              SolubilityH₂O (10 mg/ml)
              Storage +2°C to +8°C
              Hygroscopic
              Protect from light
              Do Not Freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 year at -20°C.
              Toxicity Harmful & Carcinogenic / Teratogenic
              ReferencesSergeev, D.S., et al. 1995. Bioorg. Khim. 21, 695.
              Mulsant, P., et al. 1988. Somatic Cell and Molecular Genetics 14, 243.
              Ehrenfeld, G.M., et al. 1987. Biochemistry 26, 931.
              Takita, T., et al. 1972. J. Antibiot. 25, 755.