504463 BINA - CAS 866823-73-6 - Calbiochem

BINA - CAS 866823-73-6 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Biphenyl-indanone A

Primary Target: mGlu₂
504463
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₃₀H₃₀O₄ 866823-73-6

      Pricing & Availability

      Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
      5.04463.0001
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          		 Glass bottle 5 mg
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          Description
          OverviewA selective positive allosteric modulator for mGlu receptor subtype 2 (EC50 = 33.2 nM in CHO cells expressing human mGlu2). No effect on other mGlu receptor subtypes. Exhibits antipsychotic and anxiolytic properties in mice.
          Catalogue Number504463
          Brand Family Calbiochem®
          SynonymsBiphenyl-indanone A
          References
          ReferencesBonnefous, C., et al. 2005. Bioorg. Med. Chem. Lett. 15, 4354.
          Galici, R., et al. 2006. J. Pharmacol. Exp. Ther. 318, 173.
          Benneyworth, M., et al. 2007. Mol. Pharmacol. 72, 477.
          Sheffler, D., et al. 2011. ACS Chem. Neurosci. 2, 382.
          Product Information
          CAS number866823-73-6
          FormWhite powder
          Hill FormulaC₃₀H₃₀O₄
          Chemical formulaC₃₀H₃₀O₄
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Primary TargetmGlu₂
          Purity≥98% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          BINA - CAS 866823-73-6 - Calbiochem SDS

          Title

          Safety Data Sheet (SDS) 

          References

          Reference overview
          Bonnefous, C., et al. 2005. Bioorg. Med. Chem. Lett. 15, 4354.
          Galici, R., et al. 2006. J. Pharmacol. Exp. Ther. 318, 173.
          Benneyworth, M., et al. 2007. Mol. Pharmacol. 72, 477.
          Sheffler, D., et al. 2011. ACS Chem. Neurosci. 2, 382.

          Brochure

          Title
          Pathways and Biomarkers of Glutamatergic Synapse Flyer (EMD)
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision28-June-2013 JSW
          SynonymsBiphenyl-indanone A
          DescriptionA selective positive allosteric modulator for mGlu receptor subtype 2 (EC50 = 33.2 nM in CHO cells expressing human mGlu2). No effect on other mGlu receptor subtypes. Exhibits antipsychotic and anxiolytic properties in mice.
          FormWhite powder
          CAS number866823-73-6
          Chemical formulaC₃₀H₃₀O₄
          Structure formulaStructure formula
          Purity≥98% by HPLC
          SolubilityDMSO (18 mg/ml)
          Storage +2°C to +8°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesBonnefous, C., et al. 2005. Bioorg. Med. Chem. Lett. 15, 4354.
          Galici, R., et al. 2006. J. Pharmacol. Exp. Ther. 318, 173.
          Benneyworth, M., et al. 2007. Mol. Pharmacol. 72, 477.
          Sheffler, D., et al. 2011. ACS Chem. Neurosci. 2, 382.