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07-442-AF647 Anti-trimethyl Histone H3 (Lys9) Antibody, Alexa Fluor® 647 Conjugate

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07-442-AF647
100 µL  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HICCRbAlexaFluor®647Polyclonal Antibody
      Description
      Catalogue Number07-442-AF647
      DescriptionAnti-trimethyl Histone H3 (Lys9) Antibody, Alexa Fluor® 647 Conjugate
      Background InformationHistone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
      References
      Product Information
      FormatAlexaFluor®647
      PresentationPurified rabbit conjugate in buffer containing PBS, 15 mg/mL BSA, and 0.1 % Sodium Azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-trimethyl Histone H3 (Lys9) Antibody, Alexa Fluor® 647 Conjugate is validated for use in ICC for the detection of trimethyl Histone H3 (Lys9).
      Key Applications
      • Immunocytochemistry
      Biological Information
      ImmunogenLinear peptide corresponding to Histone H3 trimethylated at Lys9.
      Concentration0.5 mg/mL
      HostRabbit
      Species Reactivity
      • Human
      Species Reactivity NoteHuman. Predicted to react with Mouse, Rat, and Chicken based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Purification MethodProtein A Purfied
      UniProt Number
      Molecular Weight~17 kDa observed. Refer to Cat. No. 07-442 for observed molecular weight information.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvalutated by Immunocytochemistry in HeLa cells.

      Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected trimethyl Histone H3 (Lys9) in HeLa cells.

      Alexa Fluor® is a registered trademark of Life Technologies®.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies