AB9702 Anti-Tyrosine Hydroxylase Antibody

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AB9702
500 µL  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M ICC, IHC, WB Ch Affinity Purified Polyclonal Antibody
      Description
      Catalogue NumberAB9702
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Tyrosine Hydroxylase Antibody
      Alternate Names
      • TH
      References
      Product Information
      FormatAffinity Purified
      PresentationAffinity purified chicken IgY. Two different antibodies were combined to make this product. Liquid in PBS, pH 7.2 with 0.02% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Tyrosine Hydroxylase Antibody is an antibody against Tyrosine Hydroxylase for use in IC, IH & WB.
      Key Applications
      • Immunocytochemistry
      • Immunohistochemistry
      • Western Blotting
      Application NotesImmunohistochemistry: 1:1000-1:2000 using 2% paraformaldehyde fixed tissues.
      Immunocytochemistry: 1:1000-1:2000 using 2% paraformaldehyde fixed cells.
      Western Blotting: 1:2000-1:5000

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenSynthetic peptides from human/mouse Tyrosine Hydroxylase
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostChicken
      SpecificityRecognizes Tyrosine Hydroxylase
      IsotypeIgY
      Species Reactivity
      • Human
      • Mouse
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryTyrosine hydroxylase is involved in the conversion of tyrosine to dopamine. As the rate-limiting enzyme in the synthesis of catecholamines, tyrosine hydroxylase has a key role in the physiology of adrenergic neurons.
      Gene Symbol
      • TH
      • TYH
      • EC 1.14.16.2
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P07101 # Plays an important role in the physiology of adrenergic neurons.
      COFACTOR: Fe(2+) ion.
      SIZE: 528 amino acids; 58524 Da
      TISSUE SPECIFICITY: Mainly expressed in the brain and adrenal glands.
      DISEASE: SwissProt: P07101 # Defects in TH are the cause of autosomal recessive Segawa syndrome [MIM:605407]; also known as DOPA-responsive dystonia. Typically, it begins in childhood or adolescence with progressive difficulty in walking and, in some cases, spasticity. Some cases present with parkinsonian symptoms in infancy and are referred to as autosomal recessive infantile parkinsonism.
      SIMILARITY: SwissProt: P07101 ## Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.
      Packaging Information
      Material Size500 µL
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Anti-Tyrosine Hydroxylase Antibody SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Tyrosine Hydroxylase Antibody Certificates of Analysis

      TitleLot Number
      CHICKEN ANTI-TYROSINE HYDROXYLASE AFFINITY PURIFIED POLYCLONAL ANTIBODY - 21421502142150
      CHICKEN ANTI-TYROSINE HYDROXYLASE AFFINITY PURIFIED POLYCLONAL ANTIBODY - 23874942387494
      CHICKEN ANTI-TYROSINE HYDROXYLASE AFFINITY PURIFIED POLYCLONAL ANTIBODY - 24440732444073
      CHICKEN ANTI-TYROSINE HYDROXYLASE - 31799583179958
      CHICKEN ANTI-TYROSINE HYDROXYLASE - 32010803201080
      CHICKEN ANTI-TYROSINE HYDROXYLASE - 32279043227904
      CHICKEN ANTI-TYROSINE HYDROXYLASE - 32435383243538
      CHICKEN ANTI-TYROSINE HYDROXYLASE - 32980423298042
      CHICKEN ANTI-TYROSINE HYDROXYLASE - 33231873323187
      CHICKEN ANTI-TYROSINE HYDROXYLASE - 34303453430345

      References

      Reference overviewPub Med ID
      Strain-specific genetics, anatomy and function of enteric neural serotonergic pathways in inbred mice.
      Neal, KB; Parry, LJ; Bornstein, JC
      The Journal of physiology  587  567-86  2009

      Show Abstract Full Text Article
      19064621 19064621

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies