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MABC710 Anti-TGFBR3, clone 1C5H11 Antibody

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MABC710
100 µL  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, MWB, FC, ELISAMAscitesMonoclonal Antibody
      Description
      Catalogue NumberMABC710
      DescriptionAnti-TGFBR3, clone 1C5H11 Antibody
      Alternate Names
      • Transforming growth factor beta receptor type 3
      • TGF-beta receptor type 3
      • TGFR-3
      • Betaglycan
      • Transforming growth factor beta receptor III
      • TGF-beta receptor type III
      • TGFBR3
      Background InformationTransforming growth factor beta receptor type 3 (TGF-beta receptor type 3 or TGFR-3), also known as Betaglycan or Transforming growth factor beta receptor III (TGF-beta receptor type III), and encoded by the gene name TGFBR3, is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. TGFBR3 is extensively modified by glycosaminoglycan groups (GAG).
      References
      Product Information
      FormatAscites
      PresentationMouse monoclonal IgG2b ascitic fluid containing up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-TGFBR3, clone 1C5H11 Antibody is an antibody against TGFBR3 for use in western blotting, flow cytometry & ELISA.
      Key Applications
      • Western Blotting
      • Flow Cytometry
      • ELISA
      Application NotesFlow Cytometry Analysis: A 1:200-1:400 dilution from a representative lot detected TGFBR3 in MOLT4 cells.

      ELISA: A representative lot was used on Control Antigen (100 ng) and Antigen (10 ng, 50 ng, 100 ng) in ELISA (Direct).



      Biological Information
      ImmunogenPurified recombinant fragment of human TGFBR3 expressed in E. Coli
      Clone1C5H11
      HostMouse
      IsotypeIgG2b
      Species Reactivity
      • Human
      • Mouse
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • TGFBR3
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight~93 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in Jurkat, HeLa, MCF-7, F9, SK-N-SH and NIH/3T3 cell lysates.

      Western Blotting Analysis: A 1:500-1:2,000 dilution of this antibody detected TGFBR3 in Jurkat, HeLa, MCF-7, F9, SK-N-SH and NIH/3T3 cell lysates.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Anti-TGFBR3, clone 1C5H11 Antibody SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-TGFBR3, clone 1C5H11 Antibody Certificates of Analysis

      TitleLot Number
      Anti-TGFBR3, clone 1C5H11 - QVP1312040 QVP1312040
      Anti-TGFBR3, clone 1C5H11 - VP1408061 VP1408061
      Anti-TGFBR3, clone 1C5H11 - VP1711172 VP1711172
      Anti-TGFBR3, clone 1C5H11 -VP1505226 VP1505226
      Anti-TGFBR3, clone 1C5H11 -VP1608036 VP1608036
      Anti-TGFBR3, clone 1C5H11 Monoclonal Antibody VP1702021
      Anti-TGFBR3, clone 1C5H11 Monoclonal Antibody VP1808171