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AB5603-AF647 Anti-Sox2 Antibody, Alexa Fluor® 647 Conjugate

AB5603-AF647
100 µL  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, MICCRbAlexaFluor®555Polyclonal Antibody
      Description
      Catalogue NumberAB5603-AF647
      DescriptionAnti-Sox2 Antibody, Alexa Fluor® 647 Conjugate
      Alternate Names
      • Transcription factor SOX-2
      • Sex determining region Y-box 2
      • SRY-related HMG-box gene 2
      • Transcription factor SOX2
      Background InformationTranscription factor SOX-2 (UniProt P48431; also known as Sex determining region Y-box 2, SRY-related HMG-box gene 2, Transcription factor SOX2) is encoded by the SOX2 (also known as ANOP3, MCOPS3) gene (Gene ID 6657) in human. Sox family of genes are related to the mammalian sex determining gene SRY. These genes contain sequences that encode for the HMG-box domains that mediate sequence-specific DNA binding. Sox genes encode transcriptional regulators involved in cell fate decision during development and the control of diverse developmental processes. At least 30 Sox genes have been identified. Sox2 plays an essential role in maintaining the pluripotency and self-renewal of undifferentiated embryonic stem cells.
      References
      Product Information
      FormatAlexaFluor®555
      PresentationPurified rabbit polyclonal antibody conjugate in PBS with 15 mg/mL BSA and 0.1 % sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-Sox2 Antibody, Alexa Fluor® 647 Conjugate is validated for use in Immunocytochemistry for the detection of Sox2.
      Key Applications
      • Immunocytochemistry
      Application NotesThe unconjugated antibody (Cat. No. AB5603) is shown to be suitable also for Western blotting and immunocytochemistry applications.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to a C-terminal region sequence of human Sox2.
      EpitopeC-terminal region.
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      Species Reactivity
      • Human
      • Mouse
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • SOX2
      • ANOP3
      • MCOPS3
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~39 kDa observed.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Immunocytochemistry in mouse ESCs.

      Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected Sox2 in mouse ESCs.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies