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AB9487 Anti-Somatostatin Receptor Type 4 Antibody

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AB9487
50 µg  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HIH(P)RbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB9487
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Somatostatin Receptor Type 4 Antibody
      Alternate Names
      • SSTR4
      References
      Product Information
      FormatAffinity Purified
      PresentationAffinity purified immunoglobulin. Liquid in PBS, pH 7.7 with 0.01% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Somatostatin Receptor Type 4 Antibody is an antibody against Somatostatin Receptor Type 4 for use in IH(P).
      Key Applications
      • Immunohistochemistry (Paraffin)
      Application NotesImmunohistochemistry on paraffin embedded tissue sections.

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenSynthetic peptide from the N-terminal extracellular domain of human Somatostatin Receptor Type 4.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityRecognizes Somatostatin Receptor Type 4 [SSTR4].
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummarySomatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR4 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in fetal and adult brain and lung.
      Gene Symbol
      • SSTR4
      • SS4R
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P31391 # Receptor for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. It is functionally coupled not only to inhibition of adenylate cyclase, but also to activation of both arachidonate release and mitogen-activated protein (MAP) kinase cascade. Mediates antiproliferative action of somatostatin in tumor cells.
      SIZE: 388 amino acids; 41895 Da
      SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
      TISSUE SPECIFICITY: Specifically expressed in fetal and adult brain, lung tissue, stomach, and in lesser quantities in the kidney, pituitary and adrenals.
      SIMILARITY: SwissProt: P31391 ## Belongs to the G-protein coupled receptor 1 family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Availability by Geography
      • This product is not available for sale in Japan.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -70°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size50 µg
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Anti-Somatostatin Receptor Type 4 Antibody SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Somatostatin Receptor Type 4 Antibody Certificates of Analysis

      TitleLot Number
      RABBIT ANTI- SOMATOSTATIN RECEPTOR TYPE 4 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2378681 2378681
      RABBIT ANTI- SOMATOSTATIN RECEPTOR TYPE 4 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2453316 2453316
      RABBIT ANTI- SOMATOSTATIN RECEPTOR TYPE 4 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2287206 2287206
      RABBIT ANTI- SOMATOSTATIN RECEPTOR TYPE 4 AFFINITY PURIFIEDPOLYCLONAL ANTIBODY -2499520 2499520

      References

      Reference overviewPub Med ID
      Immunohistochemical expression and localization of somatostatin receptor subtypes in androgen ablated prostate cancer
      Mazzucchelli R, Morichetti D, Santinelli A, Scarpelli M, Bono AV, Lopez-Beltran A, Cheng L, Montironi R. Source Section of Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, Italy.
      Analytical Cellular Pathology / Cellular Oncology  33  27–36  2010

      Show Abstract
      20966542 20966542

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies