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AB9774-50UL Anti-Somatostatin Receptor Type 3 Antibody

AB9774-50UL
50 µL  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      RWBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB9774-50UL
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Somatostatin Receptor Type 3 Antibody
      Alternate Names
      • SSTR3
      References
      Product Information
      FormatAffinity Purified
      Control
      • Included free of charge with the antibody is 40 µg of control antigen (lyophilized powder). The stock solution of the antigen can be made up using 100 µL of sterile deionized water. For negative control, preincubate 1 µg of peptide with 1 µg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user
      PresentationAffinity purified immunoglobulin. Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA, and 0.05% sodium azide as a preservative. Reconstitute with 50 μL of sterile deionized water. Centrifuge antibody preparation before use (10,000 xg for 5 min).
      Quality LevelMQ100
      Applications
      ApplicationDetect Somatostatin Receptor Type 3 using this Anti-Somatostatin Receptor Type 3 Antibody validated for use in WB.
      Key Applications
      • Western Blotting
      Application NotesWestern blot: 1:200 using ECL on rat brain lysate.
      Dilutions should be made using a carrier protein such as BSA (1-3%).
      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenPurified peptide from amino acids 233-246 of rat SSTR3.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityRecognizes Somatostatin Receptor Type 3 (SSTR3).
      Species Reactivity
      • Rat
      Species Reactivity NoteThe immunogen sequence is identical in mouse and 11 of 14 amino acids identical in human.
      Antibody TypePolyclonal Antibody
      Entrez Gene SummarySomatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biological effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR3 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in brain and pancreatic islets. SSTR3 is functionally coupled to adenylyl cyclase.
      Gene Symbol
      • SS3R
      • SSR3
      • SSR28
      • SSTR3
      Purification MethodImmunoAffinity Purified
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P32745 # Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase.
      SIZE: 418 amino acids; 45847 Da
      SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein (By similarity). Note=Internalized into endoplasmic vesicles upon somatostatin-stimulation (By similarity).
      TISSUE SPECIFICITY: Brain, pituitary and pancreas.
      PTM: Phosphorylated. Phosphorylation increases upon somatostatin binding (By similarity).
      SIMILARITY: SwissProt: P32745 ## Belongs to the G-protein coupled receptor 1 family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain lyophilized material at -20°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size50 µL
      Transport Information
      Supplemental Information
      Specifications

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies