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AB9486 Anti-Somatostatin Receptor Type 2 Antibody

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AB9486
50 µg  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HIH(P)RbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB9486
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Somatostatin Receptor Type 2 Antibody
      Alternate Names
      • SSTR2
      References
      Product Information
      FormatAffinity Purified
      PresentationAffinity purified immunoglobulin. Liquid in PBS, pH 7.7 with 0.01% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect Somatostatin Receptor Type 2 using this Anti-Somatostatin Receptor Type 2 Antibody validated for use in IH(P).
      Key Applications
      • Immunohistochemistry (Paraffin)
      Application NotesImmunohistochemistry on paraffin embedded tissue sections.

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenSynthetic peptide from the 2nd extracellular domain of human Somatostatin Receptor Type 2.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityRecognizes Somatostatin Receptor Type 2 [SSTR2].
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • SS2R
      • SRIF-1
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P30874 # Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels.
      SIZE: 369 amino acids; 41333 Da
      SUBUNIT:The C-terminus interacts with SHANK1 PDZ domain
      SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein
      TISSUE SPECIFICITY: Cerebrum and kidney. In lesser amounts in jejunum, colon and liver.
      SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Availability by Geography
      • This product is not available for sale in Japan.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -70°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size50 µg
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Anti-Somatostatin Receptor Type 2 Antibody SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Somatostatin Receptor Type 2 Antibody Certificates of Analysis

      TitleLot Number
      RABBIT ANTI- SOMATOSTATIN RECEPTOR TYPE 2 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2393842 2393842
      RABBIT ANTI- SOMATOSTATIN RECEPTOR TYPE 2 - 3323138 3323138
      RABBIT ANTI- SOMATOSTATIN RECEPTOR TYPE 2 AFFINITY PURIFIED POLYCLONAL ANTIBODY -

      References

      Reference overviewPub Med ID
      Immunohistochemical expression and localization of somatostatin receptor subtypes in androgen ablated prostate cancer
      Mazzucchelli R, Morichetti D, Santinelli A, Scarpelli M, Bono AV, Lopez-Beltran A, Cheng L, Montironi R. Source Section of Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, Italy.
      Analytical Cellular Pathology / Cellular Oncology  33  27–36  2010

      Show Abstract
      20966542 20966542