ABN485 Anti-SIPA1L1 Antibody

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ABN485
100 µg  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, R WB, IHC Rb Affinity Purified Polyclonal Antibody
      Description
      Catalogue NumberABN485
      DescriptionAnti-SIPA1L1 Antibody
      Alternate Names
      • Signal-induced proliferation associated-like protein 1
      • SIPA1-like protein 1
      • E6TP1
      • High-risk human papilloma viruses E6 oncoproteins targeted protein 1
      • E6-targeted protein 1
      • SIPA1L1
      Background InformationSignal-induced proliferation associated-like protein 1 (SIPA1L1), also called High-risk human papilloma viruses E6 oncoproteins targeted protein 1 (E6-targeted protein 1) is widely expressed and bound at the carboxy-terminus by Casein kinase I epsilon (CKIe) which leads to phosphorylation. SIPA1L1 activates RAP2A GTPase activity, aids reorganization of the actin cytoskeleton, recruits DLG4 to F-actin, regulates dendritic spine morphogenesis, and plays important roles in embryo development and cell proliferation.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Rat brain tissue lysate
      PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-SIPA1L1 Antibody is a highly specific rabbit polyclonal antibody, that targets Signal-induced proliferation associated-like protein 1 & has been tested in western blotting & IHC.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: 5 µg/mL from a representative lot detected SIPA1L1 in human brain tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human SIPA1L1.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      Species Reactivity
      • Human
      • Rat
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • SIPA1L1
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~200 kDa observed. Uncharacterized bands may appear in some lysate(s). Uniprot describes 2 isoforms at ~198 kDa and ~200 kDa.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in rat brain tissue lysate.

      Western Blotting Analysis: 1 µg/mL of this antibody detected SIPA1L1 in 15µg of rat brain tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications