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MABF301 Anti-Interleukin-7/IL-7 Antibody, clone 7B1.1

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MABF301
100 µg  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, FCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABF301
      DescriptionAnti-Interleukin-7/IL-7 Antibody, clone 7B1.1
      Alternate Names
      • Interleukin-7
      • IL-7
      Background InformationThe protein named IL-7, or interleukin 7 is a hematopoietic growth factor secreted by stromal cell in the bone marrow and thymus but also produced by many other cell types including keratinocytes, epithelial cells, hepatocytes and macrophage/dendritic cells but not by classical lymphocytes. IL7 is a cytokine that has multiple functions and is critical for proper T cell maturation and lymphoid cell survival, and its expression stimulates the proliferation of B cells, T cell and NK cells. IL-7 is detected by cells via its receptor and binding results in a cascade of signals important for T cell development and for T cell survival within the periphery, as well as memory T cells. IL-7 expression is upregulated in various lymphomas and leukemias and because of its effects on T cell development IL-7 is being examined as a therapeutic agent for transplantation studies and even latent viral infection studies.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-Interleukin-7/IL-7 Antibody, clone 7B1.1 is validated for use in western blotting & flow cytometry for the detection of Interleukin-7/IL-7.
      Key Applications
      • Western Blotting
      • Flow Cytometry
      Application NotesFlow Cytometry Analysis: 1 µg of this antibody detected recombinant Interleukin-7/IL-7 in Jurkat T and Raji B lymphocytes.
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to human Interleukin-7/IL-7.
      Clone7B1.1
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      IsotypeIgG2aκ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • IL7
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~ 17 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in Interleukin 7 cell lysate.

      Western Blotting Analysis: 0.5 µg/mL of this antibody detected 0.5 µg of recombinant Interleukin-7/IL-7.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications