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ABE530 Anti-Histone-lysine N-methyltransferase SUV39H2 Antibody

Detect SUV39H1 using this rabbit polyclonal antibody, Anti-Histone-lysine N-methyltransferase SUV39H2 Antibody validated for use in western blotting & IP.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Epigenetics & Nuclear Function Research Sub-Category: Chromatin Biology Gene Symbol: SUV39H2, KMT1B UniProt Number: Q9H5I1
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ABE530
100 µg  
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      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IPRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABE530
      DescriptionAnti-Histone-lysine N-methyltransferase SUV39H2 Antibody
      Alternate Names
      • Histone-lysine N-methyltransferase SUV39H2
      • Histone-lys N-methyltransferase SUV39H2
      • Histone H3-K9 methyltransferase 2
      • H3-K9-HMTase 2
      • Lysine N-methyltransferase 1B
      • Suppressor of variegation 3-9 homolog 2
      • Su(var)3-9 homolog 2
      Background InformationHistone-lysine N-methyltransferase SUV39H2 is also called Histone H3-K9 methyltransferase 2 (H3-K9-HMTase 2), Lysine N-methyltransferase 1B, and Suppressor of variegation 3-9 homolog 2 (Su(var)3-9 homolog 2). Histone-lysine N-methyltransferase SUV39H2 is a histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate, which creates a specific tag for epigenetic transcriptional repression and directs DNA methylation at pericentric repeats. Histone-lysine N-methyltransferase SUV39H2 is involved in several processes, including cell cycle regulation, transcriptional repression, regulation of telomere length, and higher-order chromatin organization during spermatogenesis.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect SUV39H1 using this rabbit polyclonal antibody, Anti-Histone-lysine N-methyltransferase SUV39H2 Antibody validated for use in western blotting & IP.
      Key Applications
      • Western Blotting
      • Immunoprecipitation
      Application NotesImmunoprecipitation Analysis: 10 µg from a representative lot detected Histone-lys N-methyltransferase SUV39H2 in 500 µg of MDA-MB-435 cell lysate.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human Histone-lys N-methyltransferase SUV39H2.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      Species Reactivity
      • Human
      Species Reactivity NoteDemonstrated to react with Human. Predicted to react with Rhesus Macaque and Porcine based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • SUV39H2
      • KMT1B
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~51 kDa observed. Uncharacterized band(s) may be observed in some cell lysates.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human testis tissue lysate.

      Western Blotting Analysis: 2 µg/mL of this antibody detected Histone-lys N-methyltransferase SUV39H2 in 10 µg of human testis tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications