MAB350 Anti-Enkephalin Antibody, clone NOC1

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      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      Gp, Ht, R, Rb ICC, IHC M Culture Supernatant Monoclonal Antibody
      Catalogue NumberMAB350
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Enkephalin Antibody, clone NOC1
      Product Information
      FormatCulture Supernatant
      Quality LevelMQ100
      ApplicationDetect Enkephalin using this Anti-Enkephalin Antibody, clone NOC1 validated for use in IC, IH.
      Key Applications
      • Immunocytochemistry
      • Immunohistochemistry
      Application NotesImmunohistochemistry: 1:100-1:400 on 10 μm cryostat sections of rat and guinea-pig brain stem using fluorescently labled secondary antibodies for detection (Cuello, 1984; MacMillan and Cuello, 1986).

      Immunocytochemistry: 1:300 on primary cultures of rat striatal and hippocampal neurons using a Cy2 or Cy3 conjugated secondary antibody for detection (Saudou, 1998).

      Radioimmunoassay (Cuello, 1984)

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenLeu5-enkephalin conjugated to BSA.
      SpecificityMet5- and Leu5-enkephalin. Displays about 40% cross-reactivity with C-terminal extended Met-enkephalin hexapeptides and 7% cross-reactivity with the extended heptapeptide (-Arg-Phe-OH) but does not recognize pro-enkephalin or other endogenous peptides (Cuello, 1984). By immunohistochemistry the antibody lables all sites that are known to exppress enkephalin and shows no cross-reactivity to beta-endorphin or dynorphin (Cuello, 1984; MacMillan and Cuello, 1986).
      Species Reactivity
      • Guinea Pig
      • Hamster
      • Rat
      • Rabbit
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • CEBPZ
      • CTF2
      • CBF
      • NOC1
      • CBF2
      • HSP-CBF
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q03701 # Stimulates transcription from the HSP70 promoter.
      SIZE: 1054 amino acids; 120988 Da
      SIMILARITY: SwissProt: Q03701 ## Belongs to the CBF/MAK21 family.
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information


      Anti-Enkephalin Antibody, clone NOC1 SDS


      Safety Data Sheet (SDS) 

      Anti-Enkephalin Antibody, clone NOC1 Certificates of Analysis

      TitleLot Number
      MOUSE ANTI-ENKEPHALIN - 25287632528763
      MOUSE ANTI-ENKEPHALIN - 32471153247115
      MOUSE ANTI-ENKEPHALIN - 34605363460536
      MOUSE ANTI-ENKEPHALIN -25824862582486
      MOUSE ANTI-ENKEPHALIN -26038502603850
      MOUSE ANTI-ENKEPHALIN -26330352633035
      MOUSE ANTI-ENKEPHALIN -26849502684950
      MOUSE ANTI-ENKEPHALIN -26952612695261
      MOUSE ANTI-ENKEPHALIN -27394952739495


      Reference overviewApplicationPub Med ID
      Electroacupuncture modulation of reflex hypertension in rats: role of cholecystokinin octapeptide.
      Li, M; Tjen-A-Looi, SC; Guo, ZL; Longhurst, JC
      American journal of physiology. Regulatory, integrative and comparative physiology  305  R404-13  2013

      Show Abstract
      23785073 23785073
      Down-regulation of CXCL12 by DNA hypermethylation and its involvement in gastric cancer metastatic progression.
      Yu Zhi,Jing Chen,Shuanglong Zhang,Xiaojing Chang,Jingguo Ma,Dongqiu Dai
      Digestive diseases and sciences  57  2012

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      Chemical phenotypes of P2X2 purinoreceptor immunoreactive cell bodies in the area postrema.
      Mangano, C; Colldén, G; Meister, B
      Purinergic signalling  8  223-34  2012

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      22038573 22038573
      Nucleus ambiguus cholinergic neurons activated by acupuncture: relation to enkephalin.
      Guo, ZL; Li, M; Longhurst, JC
      Brain research  1442  25-35  2012

      Show Abstract
      Immunohistochemistry22306033 22306033
      Lack of P-selectin glycoprotein ligand-1 protects mice from thrombosis after collagen/epinephrine challenge.
      Kornél Miszti-Blasius,Ildikó Beke Debreceni,Szabolcs Felszeghy,Balázs Dezso,János Kappelmayer
      Thrombosis research  127  2011

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      21237501 21237501
      Identification of urocortin 3 afferent projection to the ventromedial nucleus of the hypothalamus in rat brain.
      Chen, P; Lin, D; Giesler, J; Li, C
      The Journal of comparative neurology  519  2023-42  2011

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      21452217 21452217
      Expression pattern of stromal cell-derived factor-1 chemokine in invasive breast cancer is correlated with estrogen receptor status and patient prognosis.
      Takayuki Kobayashi,Hitoshi Tsuda,Tomoyuki Moriya,Tamio Yamasaki,Ryoko Kikuchi,Shigeto Ueda,Jiro Omata,Junji Yamamoto,Osamu Matsubara
      Breast cancer research and treatment  123  2010

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      Plasticity of lumbosacral propriospinal neurons is associated with the development of autonomic dysreflexia after thoracic spinal cord transection.
      Shaoping Hou,Hanad Duale,Adrian A Cameron,Sarah M Abshire,Travis S Lyttle,Alexander G Rabchevsky
      The Journal of comparative neurology  509  2008

      Show Abstract Full Text Article
      18512692 18512692
      Immunohistochemical features of substance P-immunoreactive chromaffin cells and nerve fibers in the rat adrenal gland.
      Hiroshi Murabayashi,Hirofumi Kuramoto,Hitoshi Kawano,Motoki Sasaki,Nobuo Kitamura,Kiyoshi Miyakawa,Kunio Tanaka,Yukio Oomori
      Archives of histology and cytology  70  2007

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      18079587 18079587
      Metabotropic glutamate receptors modulate the NMDA- and AMPA-induced gene expression in neocortical interneurons.
      Lindemeyer, K; Leemhuis, J; Löffler, S; Grass, N; Nörenberg, W; Meyer, DK
      Cerebral cortex (New York, N.Y. : 1991)  16  1662-77  2006

      Show Abstract
      16407481 16407481