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ABT127 Anti-ERp44 Antibody

ABT127
100 µg  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, RIHC, WBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABT127
      DescriptionAnti-ERp44 Antibody
      Alternate Names
      • Endoplasmic reticulum resident protein 44
      • ER protein 44
      • ERp44
      • Thioredoxin domain-containing protein 4
      Background InformationEndoplasmic reticulum resident protein 44 (ERp44) also known as thioredoxin domain-containing protein 4 (TXNDC4) is a protein that in humans is encoded by the ERP44 gene. ERp44 is a member of the protein disulfide isomerase (PDI) family and is induced during ER stress and abundantly expressed in secretory tissue cells. Disulfide bond formation occurs in the ER and is an essential step in the structural maturation of secretory and membrane proteins. Members of the Ero1 family transfer oxidative equivalents to cargo proteins via PDI and other ER oxidoreductases.
      References
      Product Information
      FormatAffinity Purified
      Control
      • K562 cell lysate
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Applications
      ApplicationAnti-ERp44 Antibody is an antibody against ERp44 for use in IHC, Western Blotting.
      Key Applications
      • Immunohistochemistry
      • Western Blotting
      Application NotesImmunohistochemistry Analysis: A 1:500 dilution from a representative lot detected ERp44 in human kidney and human pancreas tissues.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human ERp44.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      Species Reactivity
      • Human
      • Rat
      Species Reactivity NoteDemonstrated to react with Human. Predicted to react with Rat based on 100% sequence homology. Other homologies: Mouse, Bovine, and Porcine (92% sequence homology)
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • ERP44
      • TXNDC4
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~47 kDa observed. After post-translational processing, this protein may be observed at ~44 kDa. Prior to processing, it may be observed at ~47 kDa.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in K562 cell lysate.

      Western Blot Analysis: 0.2 µg/mL of this antibody detected ERp44 in 10 µg of K562 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies