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MAB1476 Anti-Chymotrypsin Antibody, Human Pancreas

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MAB1476
100 µL  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HELISA, IHCMAscitesMonoclonal Antibody
      Description
      Catalogue NumberMAB1476
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Chymotrypsin Antibody, Human Pancreas
      Background InformationChymotrypsin is an intestinal proteolytic enzyme composed of three polypeptide chains. It is produced in the pancrease as the inactive form chymotrypsinogen (single 245 aa chain). Chymotrypsinogen is activated in the duodenum by trypin and other active chymotrypsin molecules. It preferentially catalyzes the hydrolysis of peptide bonds involving L-isomers of tyrosine, phenylalanine and tryptophan. It also readily acts upon amides and esters of susceptible amino acids. Chymotrypsin catalyzes the hydrolysis of bonds of leucyl, methionyl, asparaginyl and glutamyl residues.
      References
      Product Information
      FormatAscites
      PresentationLiquid. Contains no preservative.
      Quality LevelMQ100
      Applications
      ApplicationDetect Chymotrypsin using this Anti-Chymotrypsin Antibody, Human Pancreas validated for use in ELISA, IH.
      Key Applications
      • ELISA
      • Immunohistochemistry
      Application NotesELISA

      Immunohistochemistry: 1:1000.

      Optimal working dilution must be determined by the end user.
      Biological Information
      ImmunogenPurified human pancreatic chymotrypsin.
      HostMouse
      SpecificityRecognizes chymotrypsin.
      IsotypeIgG3
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • CTRL
      • CTRL1
      • chymotrypsin-like
      • MGC70821
      • EC 3.4.21.-
      UniProt Number
      UniProt SummarySIZE: 264 amino acids; 28002 Da
      SIMILARITY: SwissProt: P40313 ## Belongs to the peptidase S1 family. & Contains 1 peptidase S1 domain.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -20°C in convenient aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles.

      During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200μL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container's cap.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Anti-Chymotrypsin Antibody, Human Pancreas SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Chymotrypsin Antibody, Human Pancreas Certificates of Analysis

      TitleLot Number
      MOUSE ANTI-CHYMOTRYPSIN MONOCLONAL ANTIBODY - 2135051 2135051
      MOUSE ANTI-CHYMOTRYPSIN MONOCLONAL ANTIBODY - 2390366 2390366
      MOUSE ANTI-CHYMOTRYPSIN - 2558427 2558427
      MOUSE ANTI-CHYMOTRYPSIN - 3173559 3173559
      MOUSE ANTI-CHYMOTRYPSIN - 3311954 3311954
      MOUSE ANTI-CHYMOTRYPSIN - 3574575 3574575
      MOUSE ANTI-CHYMOTRYPSIN - 3726151 3726151
      MOUSE ANTI-CHYMOTRYPSIN -2576356 2576356
      MOUSE ANTI-CHYMOTRYPSIN -2586827 2586827
      MOUSE ANTI-CHYMOTRYPSIN -2659244 2659244

      References

      Reference overviewPub Med ID
      Pancreatic serous microcystic adenoma with extensive oncocytic change.
      Takashi Akiyama,Yoshito Sadahira,Isao Irei,Hirotake Nishimura,Akira I Hida,Kenji Notohara,Shuji Hamazaki
      Pathology international  59  2009

      Show Abstract
      19154264 19154264
      Fibronectin fragments promote human retinal endothelial cell adhesion and proliferation and ERK activation through alpha5beta1 integrin and PI 3-kinase
      Wilson, Sylvia H, et al
      Invest Ophthalmol Vis Sci, 44:1704-15 (2003)  2003

      12657612 12657612
      Detection of human T-lymphotropic virus type I p40tax protein in cerebrospinal fluid cells from patients with human T-lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis
      Moritoyo, T. et al.
      J Neurovirol. , 5:241-248 (1999)  1999

      10414514 10414514