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ABT129 Anti-Calponin-1 Antibody

This Anti-Calponin-1 Antibody is validated for use in Western Blotting, IHC(P), Immunofluorescence for the detection of Calponin-1.

Anti-Calponin-1 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Cell Structure Research Sub-Category: Cytoskeleton Gene Symbol: CNN1 UniProt Number: P51911
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ABT129
100 µg  
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      Overview

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      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IH(P), IFRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABT129
      Replaces04-589
      DescriptionAnti-Calponin-1 Antibody
      Alternate Names
      • Calponin-1
      • Basic calponin
      • Calponin H1, smooth muscle
      Background InformationCalponin 1 is a 34 kDa protein that is predominantly found in smooth muscle tissue. It is a high-affinity actin-binding protein, but also interacts with tropomyosin, and calmodulin to modulate muscle contraction. When bound to F-actin, it inhibits the activity of the actin-activated myosin ATPase. Calponin 1 is regulated by reversible phosphorylation involving PKC and CAMKII kinases, and type 2A phosphatases. In non-muscle cells, calponin 1 may play a role in cell migration, motility, and proliferation.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Human aortic smooth muscle tissue
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-Calponin-1 Antibody is validated for use in Western Blotting, IHC(P), Immunofluorescence for the detection of Calponin-1.
      Key Applications
      • Western Blotting
      • Immunohistochemistry (Paraffin)
      • Immunofluorescence
      Application NotesImmunohistochemistry Analysis: A 1:1,000 dilution from a reprsesentative lot detected Calponin-1 in human seminal vesicle tissue.

      Immunofluorescence Analysis: A 1:500 dilution from a representative lot detected Calponin-1 in smooth muscle cells from human seminal vesicle tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the C-terminus of human Calponin-1.
      EpitopeC-terminus
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody recognizes the C-terminus of Calponin-1.
      Species Reactivity
      • Human
      Species Reactivity NoteDemonstrated to react with Human. Predicted to react with Bovine, Chimpanzee, and Sheep based on 100% sequence homology. Other homologies: Rat (92% sequence homology) and Mouse (83% sequence homology).
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • CNN1
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~33 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in human aortic smooth muscle tissue.

      Western Blot Analysis: 0.1 µg/mL of this antibody detected Calponin-1 in human aortic smooth muscle tissue.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      ABT129 04053252599927

      Documentation

      Anti-Calponin-1 Antibody SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Calponin-1 Antibody Certificates of Analysis

      TitleLot Number
      Anti-Calponin-1 2484064
      Anti-Calponin-1 - 3227310 3227310
      Anti-Calponin-1 - 3439695 3439695
      Anti-Calponin-1 - 4108268 4108268
      Anti-Calponin-1 - Q2055263 Q2055263
      Anti-Calponin-1 -2659365 2659365
      Anti-Calponin-1 -2683272 2683272
      Anti-Calponin-1 -2799095 2799095
      Anti-Calponin-1 Polyclonal Antibody 2949175
      Anti-Calponin-1 Polyclonal Antibody 3054704
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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies