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MABT200 Anti-COL1A2, clone alpha2CT, Azide Free Antibody

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MABT200
100 µg  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HIHC, ACTMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABT200
      DescriptionAnti-COL1A2, clone alpha2CT, Azide Free Antibody
      Alternate Names
      • Annexin A6
      • 67 kDa calelectrin
      • Annexin VI
      • Annexin-6
      • Calphobindin-II
      • CPB-II
      • Lipocortin VI
      • Protein III
      • p68
      • p70
      Background InformationCollagens are major fibrous structural elements of cartilage, tendon, bone, skin, lung, and blood vessels. Type I collagen, a heterotrimer consisting of two α1 chains and one α2 chain, is the most abundant fibrillar collagen. It is preferentially synthesized in bone, skin, and tendon and is the most abundant protein found in these tissues.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal IgAκ in buffer containing PBS without preservatives.
      Quality LevelMQ100
      Applications
      ApplicationAnti-COL1A2 antibody, clone alpha2CT, Azide Free is an antibody against COL1A2 for use in IHC & activity assay.
      Key Applications
      • Immunohistochemistry
      • Activity Assay
      Application NotesActivity Assay Analysis: A representative lot from an independent laboratory inhibits fibrin formation in vitro (Chung, H. J., et al. (2008). J Biol Chem. 283(38):25879-25886.).
      Biological Information
      ImmunogenLinear peptide corresponding to the C-terminus of human Collagen type I alpha 2.
      EpitopeC-terminus
      Clonealpha2CT
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      IsotypeIgAκ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • ANXA6
      • ANX6
      Purification MethodProtein L
      UniProt Number
      Molecular Weight125 and 150 kDa calculated
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Immunohistochemistry Analysis in human bone tissues.

      Immunohistochemistry Analysis: A 1:50 dilution of this antibody detected COL1A2 in human bone tissues.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Anti-COL1A2, clone alpha2CT, Azide Free Antibody SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-COL1A2, clone alpha2CT, Azide Free Antibody Certificates of Analysis

      TitleLot Number
      Anti-COL1A2, clone alpha2CT, Azide Free - 3324203 3324203
      Anti-COL1A2, clone alpha2CT, Azide Free - Q2366202 Q2366202

      References

      Reference overviewPub Med ID
      Collagen fibril formation. A new target to limit fibrosis.
      Chung, Hye Jin, et al.
      J. Biol. Chem., 283: 25879-86 (2008)  2008

      Show Abstract
      18650436 18650436