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MABN743 Anti-CALCRL Antibody, clone 9G2.1

100 µg  
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      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IHCMPurifiedMonoclonal Antibody
      Catalogue NumberMABN743
      DescriptionAnti-CALCRL Antibody, clone 9G2.1
      Alternate Names
      • calcitonin receptor-like receptor
      • CALCRL
      • Calcitonin gene-related peptide type 1 receptor
      • CGRP type 1 receptor
      • CRLR
      Background InformationCALCRL is the cell membrane receptor for the calcitonin-gene-related peptide (CGRP) together with RAMP1 (receptor activity modifying protein 1). CALCRL is also the adrenomedullin receptor but only in association with RAMP3. RAMPs are required to transport calcitonin-receptor-like receptor (CALCRL) to the plasma membrane. The CALCRL associated receptors are G-protein coupled receptors expressed in the lung and heart tissues.
      Product Information
      PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ300
      ApplicationAnti-CALCRL Antibody, clone 9G2.1 is an antibody against CALCRL for use in Immunohistochemistry and Immunocytochemistry.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesWestern Blotting Analysis: 0.5 µg/mL from a representative lot detected CALCRL in 10 µg of mouse brain, mouse cerebellum, mouse hypothalamus, and human pituitary tissue lysate.
      Immunohistochemistry Analysis: A 1:50-250 dilution from a representative lot detected CALCRL in human lung and human heart tissue.
      Biological Information
      ImmunogenLinear peptide corresponding to human CALCRL.
      ConcentrationPlease refer to lot specific datasheet.
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • CALCRL
      • CGRPR
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~55 kDa observed
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human lung tissue lysate.

      Western Blotting Analysis: 0.5 µg/mL of this antibody detected CALCRL in 10 µg of human lung tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information