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ABN14 Anti-Brain lipid binding protein Antibody

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      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M, HWB, IHCRbAffinity PurifiedPolyclonal Antibody
      Catalogue NumberABN14
      DescriptionAnti-Brain lipid binding protein Antibody
      Alternate Names
      • Brain lipid-binding protein
      • Fatty acid-binding protein 7
      • Mammary-derived growth inhibitor related
      • brain lipid binding protein
      • fatty acid binding protein 7, brain
      • mammary-derived growth inhibitor-related
      Background InformationBLBP (Brain lipid-binding protein) belongs to a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. BLBPs play essential roles in fatty acid uptake, transport and metabolism. BLBP can be used as a molecular marker for radial glia (a major neural progenitor cell type and a scaffolding supporting neuronal migration) in the developing central nervous system. Radial glia play an essential role in the generation of the cerebral cortex through their function as neuronal precursors and as neuronal migration guides.
      Product Information
      FormatAffinity Purified
      HS Code3002 15 90
      • P1 mouse brain tissue lysate
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.
      Quality LevelMQ100
      ApplicationDetect Brain lipid binding protein using this Anti-Brain lipid binding protein Antibody validated for use in WB, IH.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:300 dilution of ABN14 antibody from a previous lot detected Brain lipid binding protein in mouse cerebellum tissue.
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to human Brain lipid-binding protein.
      EpitopeCytoplasmic Domain
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      SpecificityThis antibody recognizes Brain lipid-binding protein.
      Species Reactivity
      • Mouse
      • Human
      Species Reactivity NoteProven to react with mouse. Predicted to react with human based on 100% sequence homology. Rat homology - 88%.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThe protein encoded by this gene is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs are thought to play roles in fatty acid uptake, transport, and metabolism. [provided by RefSeq].
      Gene Symbol
      • FABP7
      • B-FABP
      • MRG
      • BLBP
      • FABPB
      Purification MethodAffinity Purfied
      UniProt Number
      UniProt SummaryFUNCTION: B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers By similarity.


      TISSUE SPECIFICITY: Expressed in brain and other neural tissues.

      DOMAIN: Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.

      SEQUENCE SIMILARITIES: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
      Molecular Weight~ 15 kDa
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in P1 mouse brain tissue lysate.

      Western Blot Analysis: 0.01 µg/ml of this antibody detected Brain lipid-binding protein in 10 µg of P1 mouse brain tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Global Trade Item Number
      Catalog Number GTIN
      ABN14 04053252277825


      Anti-Brain lipid binding protein Antibody SDS


      Safety Data Sheet (SDS) 

      Anti-Brain lipid binding protein Antibody Certificates of Analysis

      TitleLot Number
      Anti-Brain lipid binding protein (rabbit polyclonal) Polyclonal Antibody Q2922272
      Anti-Brain lipid binding protein - 2137042 2137042
      Anti-Brain lipid binding protein - 2377420 2377420
      Anti-Brain lipid binding protein - 2462888 2462888
      Anti-Brain lipid binding protein - 1977633 1977633
      Anti-Brain lipid binding protein - 2020474 2020474
      Anti-Brain lipid binding protein - 2037218 2037218
      Anti-Brain lipid binding protein - 2203087 2203087
      Anti-Brain lipid binding protein - 2494022 2494022
      Anti-Brain lipid binding protein - 2887844 2887844


      Reference overviewApplicationPub Med ID
      Sox9 is critical for suppression of neurogenesis but not initiation of gliogenesis in the cerebellum.
      Vong, KI; Leung, CK; Behringer, RR; Kwan, KM
      Molecular brain  8  25  2015

      Show Abstract
      25888505 25888505
      A mouse model of human primitive neuroectodermal tumors resulting from microenvironmentally-driven malignant transformation of orthotopically transplanted radial glial cells.
      Malchenko, S; Sredni, ST; Hashimoto, H; Kasai, A; Nagayasu, K; Xie, J; Margaryan, NV; Seiriki, K; Lulla, RR; Seftor, RE; Pachman, LM; Meltzer, HY; Hendrix, MJ; Soares, MB
      PloS one  10  e0121707  2015

      Show Abstract
      Immunohistochemistry25826270 25826270
      Activation of Sonic hedgehog signaling in neural progenitor cells promotes glioma development in the zebrafish optic pathway.
      Ju, B; Chen, W; Spitsbergen, JM; Lu, J; Vogel, P; Peters, JL; Wang, YD; Orr, BA; Wu, J; Henson, HE; Jia, S; Parupalli, C; Taylor, MR
      Oncogenesis  3  e96  2014

      Show Abstract
      24686726 24686726
      Loss of Usp9x disrupts cortical architecture, hippocampal development and TGFβ-mediated axonogenesis.
      Stegeman, S; Jolly, LA; Premarathne, S; Gecz, J; Richards, LJ; Mackay-Sim, A; Wood, SA
      PloS one  8  e68287  2013

      Show Abstract
      23861879 23861879
      Apoptosis-inducing factor downregulation increased neuronal progenitor, but not stem cell, survival in the neonatal hippocampus after cerebral hypoxia-ischemia.
      Sun, Y; Zhang, Y; Wang, X; Blomgren, K; Zhu, C
      Molecular neurodegeneration  7  17  2012

      Show Abstract
      22534064 22534064
      IKKβ/NF-κB disrupts adult hypothalamic neural stem cells to mediate a neurodegenerative mechanism of dietary obesity and pre-diabetes.
      Li, J; Tang, Y; Cai, D
      Nature cell biology  14  999-1012  2012

      Show Abstract
      Immunofluorescence22940906 22940906
      Lithium reduced neural progenitor apoptosis in the hippocampus and ameliorated functional deficits after irradiation to the immature mouse brain.
      Kaiming Huo,Yanyan Sun,Hongfu Li,Xiaonan Du,Xiaoyang Wang,Niklas Karlsson,Changlian Zhu,Klas Blomgren
      Molecular and cellular neurosciences  51  2012

      Show Abstract
      22800605 22800605

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