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MAB3502-I Anti-Angiotensin Converting Enzyme Antibody, clone 2E2

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MAB3502-I
100 µL  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      RWBMCulture SupernatantMonoclonal Antibody
      Description
      Catalogue NumberMAB3502-I
      ReplacesMAB3502
      DescriptionAnti-Angiotensin Converting Enzyme Antibody, clone 2E2
      Alternate Names
      • Angiotensin-converting enzyme
      • ACE
      • Dipeptidyl carboxypeptidase I
      • Kininase II
      • CD143
      Background InformationAngiotensin-converting enzyme (ACE) is a zinc-metallopeptidase belonging to the peptidase M2 family. It catalyzes the conversion of angiotensin I to angiotensin II and the degradation of bradykinin, which increases the vasoconstrictive effects of angiotensin. The Angiotensin-converting enzyme plays an important role in maintaining cardiac function and vascular tone. It is highly expressed in the heart, lung, kidney, gastrointestinal system, and prostate. Defects in the Angiotensin-converting may contribute cardiac disease; and renal tubular dysgenesis, a condition characterized by persistent fetal anuria and perinatal death.
      References
      Product Information
      FormatCulture Supernatant
      Control
      • Rat Angiotensin Converting Enzyme
      PresentationMouse monoclonal IgG1 cultured supernatant without preservatives.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Angiotensin Converting Enzyme Antibody, clone 2E2.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenHuman Angiotensin Converting Enzyme.
      Clone2E2
      HostMouse
      IsotypeIgG1
      Species Reactivity
      • Rat
      Species Reactivity NoteDemonstrated to react with Rat. Predicted to react with Human based on immunogen design.
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • ACE
      • DCP
      • DCP1
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight~180 kDa observed. The calculated molecular weight is 150 kDa; however, this protein is known to be glycolsylated.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in rat Angiotensin Converting Enzyme.

      Western Blot Analysis: A 1:2,000 dilution of this antibody detected rat Angiotensin Converting Enzyme in WB.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies