MABT508 Anti-ARP2, clone EPR7979, Rabbit Monoclonal Antibody

MABT508
100 µL  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H WB, FC Rb Unpurified Monoclonal Antibody
      Description
      Catalogue NumberMABT508
      DescriptionAnti-ARP2, clone EPR7979, Rabbit Monoclonal Antibody
      Alternate Names
      • Actin-related protein 2
      • Actin-like protein 2
      • ACTR2
      • ARP2
      Background InformationActin-related protein 2, also known as Actin-like protein 2, and encoded by the gene name ACTR2 or ARP2, functions as an ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. ARP2 is localized to the cytoplasm.
      References
      Product Information
      FormatUnpurified
      PresentationRabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-ARP2 antibody is validated for use in WB, FC for the detection of ARP2.
      Key Applications
      • Western Blotting
      • Flow Cytometry
      Application NotesFlow Cytometry Analysis: A 1:10-100 dilution from a representative lot detected ARP2 in MCF-7 cells.

      Produced in collaboration with Epitomics™
      Biological Information
      ImmunogenSynthetic peptide corresponding to human ARP2.
      CloneEPR7979
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      SpecificityDissociation constant (KD) is 1.75 x 10-11 M
      IsotypeIgG
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • ACTR2
      • ARP2
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight~37 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in Jurkat, HUVEC, MCF-7, and HeLa cell lysates.

      Western Blotting Analysis: A 1:1,000-10,000 dilution of this antibody detected ARP2 in Jurkat, HUVEC, MCF-7, and HeLa cell lysates.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies