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ABN476 Anti-ACVR1C Antibody

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ABN476
100 µg  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABN476
      DescriptionAnti-ACVR1C Antibody
      Alternate Names
      • Activin receptor type-1C
      • Activin receptor type IC
      • ACTR-IC
      • Activin receptor-like kinase 7
      • ALK-7
      • ACVR1C
      Background InformationActivin receptor type-1 (ACVR1C) is a dimeric growth and differentiation factor belonging to the TKL Ser/Thr protein kinase family. Activins signal through a heteromeric complex of receptor serine kinases which include at least two, type I and two type II receptors. ACVR1C plays an important role in cell differentiation, growth arrest, and apoptosis. It is found in pancreas, heart, colon, small intestine, ovary, hippocampus, medulla oblongata, and putamen of the brain.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Human placenta tissue lysate
      PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect Activin receptor type-1 using this rabbit polyclonal antibody, Anti-ACVR1C Antibody validated for use in western blotting.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human ACVR1C.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • ACVR1C
      • ALK7
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~62 kDa observed. Uniprot describes 4 isoforms at ~37 kDa, ~46 kDa, ~50 kDa, and ~55 kDa. Uncharacterized bands may appear in some lysates.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human placenta tissue lysate.

      Western Blotting Analysis: 1 µg/mL of this antibody detected ACVR1C in 15 µg of human placenta tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies