H225: Highly flammable liquid and vapour. H319: Causes serious eye irritation. H336: May cause drowsiness or dizziness.
Precautionary Statement(s)
P210: Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P233: Keep container tightly closed. P240: Ground and bond container and receiving equipment. P241: Use explosion-proof electrical/ ventilating/ lighting equipment. P242: Use non-sparking tools. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
Signal Word
Danger
RTECS
NT8050000
Storage class
3 Flammable liquids
WGK
WGK 1 slightly hazardous to water
Disposal
1 Strongly contaminated halogen-free organic solvents: container A.
Safety Information
Categories of danger
highly flammable, irritant
Product Usage Statements
Storage and Shipping Information
Storage
Store at +2°C to +25°C.
Packaging Information
Transport Information
Declaration (railroad and road) ADR, RID
UN 1219 , 3, II
Declaration (transport by air) IATA-DGR
UN 1219 , 3, II
Declaration (transport by sea) IMDG-Code
UN 1219 , 3, II
Supplemental Information
Specifications
Assay (GC)
≥ 99.5 %
Identity (IR)
conforms
Identity B (USP)
conforms
Identity (JP)
conforms
Appearance
conforms
Clarity of solution
conforms
Acidity or alkalinity
conforms
Acidity
conforms
Refractive index (n 20/D)
1.376 - 1.378
Density (d 20 °C/20 °C)
0.785 - 0.788
Density (d 25 °C/25 °C)
0.783 - 0.787
Boiling range (81-83°C)
≥ 94 % (v/v)
Absorbance (at 230 nm)
≤ 0.300
Absorbance (at 250 nm)
≤ 0.100
Absorbance (at 270 nm)
≤ 0.030
Absorbance (at 290 nm)
≤ 0.020
Absorbance (at 310 nm)
≤ 0.010
The spectrum shows a steadily descending curve with no observable peaks or shoulders
conforms
Peroxides
conforms
Ni (Nickel)*
≤ 0.05 ppm
Volatile Impurities (GC) (individual)
≤ 0.1 % (v/v)
Volatile Impurities (GC) (total)
≤ 1.0 % (v/v)
Benzene and related substances (GC) (Benzene)
≤ 2 ppm
Benzene and related substances (GC) (total of impurities apart from 2-butanol)
≤ 0.3 %
Cyclohexane (GC)
≤ 50 ppm
Acetone (GC)
≤ 50 ppm
Ethanol (GC)
≤ 50 ppm
Methanol (GC)
≤ 200 ppm
1-Propylalcohol (GC)
≤ 300 ppm
Isopropylether (GC)
≤ 0.01 %
Other residual solvents (ICH Q3C)
excluded by manufacturing process
Evaporation residue
≤ 0.0020 %
Water
≤ 0.20 %
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*). Conforms to Ph Eur, BP, JP, USP
