H225: Highly flammable liquid and vapour. H319: Causes serious eye irritation. H336: May cause drowsiness or dizziness.
Precautionary Statement(s)
P210: Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P240: Ground/bond container and receiving equipment. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
Signal Word
Danger
RTECS
NT8050000
Storage class
3 Flammable liquids
WGK
WGK 1 slightly hazardous to water
Disposal
1 Strongly contaminated halogen-free organic solvents: container A.
Safety Information
Hazard Symbols
Irritant Flammable
Categories of danger
highly flammable, irritant
R Phrase
R 11-36-67 Highly flammable.Irritating to eyes.Vapours may cause drowsiness and dizziness.
S Phrase
S 7-16-24/25-26 Keep container tightly closed.Keep away from sources of ignition - No smoking.Avoid contact with skin and eyes.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Product Usage Statements
Storage and Shipping Information
Storage
Store at +2°C to +25°C.
Packaging Information
Transport Information
Declaration (railroad and road) ADR, RID
UN 1219 , 3, II
Declaration (transport by air) IATA-DGR
UN 1219 , 3, II
Declaration (transport by sea) IMDG-Code
UN 1219 , 3, II
Supplemental Information
Specifications
Assay (GC)
≥ 99.5 %
Identity (IR)
conforms
Identity B (USP)
conforms
Identity (JP)
conforms
Appearance
conforms
Clarity of solution
conforms
Acidity or alkalinity
conforms
Acidity
conforms
Refractive index (n 20/D)
1.376 - 1.378
Density (d 20 °C/20 °C)
0.785 - 0.788
Density (d 25 °C/25 °C)
0.783 - 0.787
Boiling range (81-83°C)
≥ 94 % (v/v)
Absorbance (at 230 nm)
≤ 0.300
Absorbance (at 250 nm)
≤ 0.100
Absorbance (at 270 nm)
≤ 0.030
Absorbance (at 290 nm)
≤ 0.020
Absorbance (at 310 nm)
≤ 0.010
The spectrum shows a steadily descending curve with no observable peaks or shoulders
conforms
Peroxides
conforms
Volatile Impurities (GC) (individual)
≤ 0.1 % (v/v)
Volatile Impurities (GC) (total)
≤ 1.0 % (v/v)
Benzene and related substances (GC) (Benzene)
≤ 2 ppm
Benzene and related substances (GC) (total of impurities apart from 2-butanol)
≤ 0.3 %
Cyclohexane (GC)
≤ 50 ppm
Acetone (GC)
≤ 50 ppm
Ethanol (GC)
≤ 50 ppm
1-Propylalcohol (GC)
≤ 300 ppm
Isopropylether (GC)
≤ 0.01 %
Other residual solvents (ICH Q3C)
excluded by manufacturing process
Evaporation residue
≤ 0.0020 %
Water
≤ 0.20 %
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*). Conforms to Ph Eur, BP, JP, USP