106446 tri-Sodium citrate dihydrate

Overview

Replacement Information

Key Specifications Table

CAS #EC NumberHill FormulaMolar MassGrade Value
6132-04-3 200-675-3 C₆H₅Na₃O₇ * 2 H₂O 294.10 g/mol Ph Eur,BP,JP,USP,E 331

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1064461000
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      Plastic bottle 1 kg
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      1064469012
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          Plastic Box 12 kg
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          1.06446.9029
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              Double PE Sack 25 kg
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              Description
              Catalogue Number106446
              SynonymsTrisodium Citrate, Sodium Citrate, Dihydrate
              References
              Product Information
              CAS number6132-04-3
              EC number200-675-3
              GradePh Eur,BP,JP,USP,E 331
              Hill FormulaC₆H₅Na₃O₇ * 2 H₂O
              Molar Mass294.10 g/mol
              HS Code2918 15 00
              Structure formula ImageStructure formula Image
              Quality LevelMQ500
              Applications
              Biological Information
              Physicochemical Information
              Melting Point150 °C (anhydrous substance)
              pH value7.5 - 9.0 (50 g/l, H₂O, 25 °C)
              Bulk density600 kg/m3
              Solubility720 g/l
              Dimensions
              Materials Information
              Toxicological Information
              LD 50 oralLD50 Rat > 8000 mg/kg
              Safety Information according to GHS
              Storage class10 - 13 Other liquids and solids
              WGKWGK 1 slightly hazardous to water
              Disposal3
              Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
              Safety Information
              Product Usage Statements
              Storage and Shipping Information
              StorageStorage temperature: no restrictions.
              Packaging Information
              Transport Information
              Declaration (railroad and road) ADR, RIDKein Gefahrgut
              Declaration (transport by air) IATA-DGRNo Dangerous Good
              Declaration (transport by sea) IMDG-CodeNo Dangerous Good
              Supplemental Information
              Specifications
              Assay (Perchloric acid titration, calc. on anhydrous substance (Ph Eur))99.0 - 101.0 %
              Assay (Perchloric acid titration, previously dried substance) (JP/USP)99.0 - 100.5 %
              Identity (Na)passes test
              Identity (Citrate)passes test
              Identity (reaction upon ignition)passes test
              Appearancewhite to almost white, crystalline powder
              Appearance of solution (100 g/l, CO₂-free water)clear and colorless
              Acidity or alkalinitypasses test
              pH (50 g/l CO₂-free water)7.5 - 8.5
              Chloride (Cl)≤ 50 ppm
              Sulfate (SO₄)≤ 150 ppm
              Heavy metals (as Pb)≤ 5 ppm
              Al (Aluminium)≤ 5 ppm
              Al (Aluminium) (ICP)≤ 5 ppm
              As (Arsenic)≤ 1 ppm
              As (Arsenic) (ICP)≤ 1 ppm
              Hg (Mercury)≤ 1 ppm
              Pb (Lead)≤ 1 ppm
              Pb (Lead) (ICP)≤ 1 ppm
              Oxalate (as C₂H₂O₄)≤ 100 ppm
              Tartrate (C₄H₄O₆)passes test
              Residual solvents (ICH Q3C)excluded by manufacturing process
              Readily carbonisable substancepasses test
              Water (according to Karl Fischer)11.0 - 13.0 %
              Loss on drying (180 °C, 18 h)10.0 - 13.0 %
              Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
              Corresponds to Ph. Eur., BP, JP, USP, E 331
              Conforms to the purity criteria on food additives according to the current European Commission Regulation.

              Documentation

              Material Qualification Dossier

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              Quality Management Dossier

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              Operational Excellence Dossier

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              tri-Sodium citrate dihydrate SDS

              Title

              Safety Data Sheet (SDS) 

              tri-Sodium citrate dihydrate Certificates of Analysis

              Product Number PackagingSpecificationLot Number
              1064461000 Plastic bottlePDF Specification Document
              1064469012 Plastic BoxPDF Specification Document
              1.06446.9029 Double PE SackPDF Specification Document

              Certificates

              Title