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504374 ZK-756326 - CAS 874911-96-3 - Calbiochem

504374
  
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      Overview

      Replacement Information

      Key Specifications Table

      CAS #Empirical Formula
      874911-96-3C₂₁H₂₈N₂O₃•2HCl
      Description
      OverviewA highly potent and selective agonist for chemokine receptor 8 (CCR8) (IC50 values are 1.8 and 2.6 µM for human and mouse receptors respectively). Induces chemotaxis and inhibits Env-mediated (HIV) cell-cell fusion.
      Catalogue Number504374
      Brand Family Calbiochem®
      Synonyms2-[2-[4-[(3-phenoxyphenyl)methyl]-1-piperazinyl]ethoxy]ethanol dihydrochloride, ZK756326, ZK 756326
      References
      ReferencesHaskell, C., et al. 2006. Mol Pharmacol. 69, 309.
      Product Information
      CAS number874911-96-3
      FormWhite solid
      Hill FormulaC₂₁H₂₈N₂O₃•2HCl
      Chemical formulaC₂₁H₂₈N₂O₃•2HCl
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetCCR8
      Purity≥98% by TLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +15°C to +30°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      References

      Reference overview
      Haskell, C., et al. 2006. Mol Pharmacol. 69, 309.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision26-July-2013 JSW
      Synonyms2-[2-[4-[(3-phenoxyphenyl)methyl]-1-piperazinyl]ethoxy]ethanol dihydrochloride, ZK756326, ZK 756326
      DescriptionA highly potent and selective agonist for chemokine receptor 8 (CCR8) (IC50 values are 1.8 and 2.6 µM for human and mouse receptors respectively). Induces chemotaxis and inhibits Env-mediated (HIV) cell-cell fusion.
      FormWhite solid
      CAS number874911-96-3
      Chemical formulaC₂₁H₂₈N₂O₃•2HCl
      Structure formulaStructure formula
      Purity≥98% by TLC
      SolubilityH₂O
      Storage Protect from light
      +15°C to +30°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesHaskell, C., et al. 2006. Mol Pharmacol. 69, 309.