676950 Veratridine - CAS 71-62-5 - Calbiochem

A Na+ channel opener.

Veratridine - CAS 71-62-5 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Primary Target: Na+ channel
676950
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₃₆H₅₁NO₁₁ 71-62-5

      Pricing & Availability

      Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
      676950-5MG
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          		 Alu drum 5 mg
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          Description
          OverviewA Na+ channel opener. Increases intracellular Ca2+ levels without affecting Na+ - Ca2+ exchange. Acts at neurotoxin receptor site 2 and preferentially binds to activated Na+ channels causing persistent activation. Induces cell death in bovine chromaffin cells.
          Catalogue Number676950
          Brand Family Calbiochem®
          References
          ReferencesMaroto, R., et al. 1994. Eur. J. Pharmacol. 270, 331.
          Plattner, H., et al. 1994. J. Membr. Biol. 142, 229.
          Rando, T.A., et al. 1989. J. Gen. Physiol. 93, 43.
          Rando, T.A., et al. 1986. Mol. Pharmacol. 29, 467.
          Product Information
          CAS number71-62-5
          ATP CompetitiveN
          FormWhite to yellow solid
          Hill FormulaC₃₆H₅₁NO₁₁
          Chemical formulaC₃₆H₅₁NO₁₁
          ReversibleN
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Primary TargetNa+ channel
          Purity≥98% by TLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSYX5600000
          Safety Information
          R PhraseR: 26/27/28

          Very toxic by inhalation, in contact with skin and if swallowed.
          S PhraseS: 26-36/37/39-45

          In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
          Wear suitable protective clothing, gloves and eye/face protection.
          In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Highly Toxic
          Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
          Storage +2°C to +8°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Veratridine - CAS 71-62-5 - Calbiochem SDS

          Title

          Safety Data Sheet (SDS) 

          Veratridine - CAS 71-62-5 - Calbiochem Certificates of Analysis

          TitleLot Number
          676950

          References

          Reference overview
          Maroto, R., et al. 1994. Eur. J. Pharmacol. 270, 331.
          Plattner, H., et al. 1994. J. Membr. Biol. 142, 229.
          Rando, T.A., et al. 1989. J. Gen. Physiol. 93, 43.
          Rando, T.A., et al. 1986. Mol. Pharmacol. 29, 467.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision22-January-2018 JSW
          DescriptionA Na+ channel opener. Increases intracellular Ca2+ levels without affecting Na+-Ca2+ exchange. Acts at neurotoxin receptor site 2 and preferentially binds to activated Na+ channels causing persistent activation. Induces cell death in bovine chromaffin cells.
          FormWhite to yellow solid
          CAS number71-62-5
          RTECSYX5600000
          Chemical formulaC₃₆H₅₁NO₁₁
          Structure formulaStructure formula
          Purity≥98% by TLC
          SolubilityDMSO (25 mg/ml) or Ethanol (25 mg/ml)
          Storage +2°C to +8°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Highly Toxic
          Merck USA index14, 9954
          ReferencesMaroto, R., et al. 1994. Eur. J. Pharmacol. 270, 331.
          Plattner, H., et al. 1994. J. Membr. Biol. 142, 229.
          Rando, T.A., et al. 1989. J. Gen. Physiol. 93, 43.
          Rando, T.A., et al. 1986. Mol. Pharmacol. 29, 467.