Millipore Sigma Vibrant Logo

108386 Tris(hydroxymethyl)aminomethane

Overview

Replacement Information

Key Specifications Table

CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
77-86-1201-064-4C₄H₁₁NO₃H₂NC(CH₂OH)₃121.14 g/molPh Eur,BP,ChP,JPC,USP

Pricing & Availability

Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
1083865000
Retrieving availability...
Limited AvailabilityLimited Availability
Stocked 
Discontinued
Limited Quantities Available
Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      Plastic bottle 5 kg
      Retrieving price...
      Price could not be retrieved
      Minimum Quantity is a multiple of
      Maximum Quantity is
      Upon Order Completion More Information
      You Saved ()
       
      Request Pricing
      1083869025
      Retrieving availability...
      Limited AvailabilityLimited Availability
      Stocked 
      Discontinued
      Limited Quantities Available
      Available
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service
          Contact Customer Service

          25 kg
          Retrieving price...
          Price could not be retrieved
          Minimum Quantity is a multiple of
          Maximum Quantity is
          Upon Order Completion More Information
          You Saved ()
           
          Request Pricing
          Description
          Catalogue Number108386
          SynonymsTrometamol, Aminomethylidine trimethanol, 2-Amino-2-hydroxymethyl-1.3-propanediol, TRIS-buffer
          DescriptionTris(hydroxymethyl)aminomethane
          References
          Product Information
          CAS number77-86-1
          EC number201-064-4
          GradePh Eur,BP,ChP,JPC,USP
          Hill FormulaC₄H₁₁NO₃
          Chemical formulaH₂NC(CH₂OH)₃
          Molar Mass121.14 g/mol
          HS Code2922 19 00
          Structure formula ImageStructure formula Image
          Quality LevelMQ500
          Applications
          Biological Information
          Physicochemical Information
          Boiling point219 - 220 °C (13.3 hPa)
          Density1.32 g/cm3 (20 °C)
          Melting Point169 °C
          pH value10.2 - 10.6 (6 g/l, H₂O, 20 °C)
          Vapor pressure<0.1 hPa (20 °C)
          Bulk density840 kg/m3
          Solubility678 g/l
          Dimensions
          Materials Information
          Toxicological Information
          LD 50 oralLD50 Rat > 5000 mg/kg
          LD 50 dermalLD50 Rat > 5000 mg/kg
          Safety Information according to GHS
          RTECSTY2900000
          Storage class10 - 13 Other liquids and solids
          WGKWGK 1 slightly hazardous to water
          Disposal3
          Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          StorageNoTempLimit
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Material Qualification Dossier

          TitleLot Number
          1.0

          Quality Management Dossier

          Title

          Operational Excellence Dossier

          Title

          Tris(hydroxymethyl)aminomethane SDS

          Title

          Safety Data Sheet (SDS) 

          Tris(hydroxymethyl)aminomethane Certificates of Analysis

          Product Number PackagingSpecificationLot Number
          1083865000 Plastic bottlePDF Specification Document
          1083869025 PDF Specification Document

          Certificates

          Title

          Related Products & Applications

          Related Products By: Application Facete

          Related Products By: Brand Facete

          Categories

          Small Molecule Pharmaceuticals > Formulation > Liquid Dosage Form > pH Adjustments and Isotonizers
          Small Molecule Pharmaceuticals > Formulation > Semisolid Dosage Form > Acidulants and pH Adjustments
          Biopharmaceutical Manufacturing > Downstream Processing > Chromatography > Process Chemicals > Buffers
          Biopharmaceutical Manufacturing > Formulation > Liquid Dosage > pH Adjustments and Isotonizers