572201 Streptozotocin - CAS 18883-66-4 - Calbiochem

572201
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Overview

Replacement Information

Key Specifications Table

Empirical FormulaCAS #
C₈H₁₅N₃O₇ 18883-66-4

Pricing & Availability

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572201-1GM
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      572201-250MG
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          Description
          OverviewAn N-nitroso-containing diabetogenic compound that acts as a nitric oxide donor in pancreatic islets. An antibiotic effective against Gram-negative bacteria. Causes DNA alkylation and DNA strand breaks in pancreatic islet cells.
          Catalogue Number572201
          Brand Family Calbiochem®
          Synonyms2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose
          References
          ReferencesKroncke, K.D., et al. 1995. Biol. Chem. Hoppe Seyler 376, 179.
          Kwon, N.S., et al. 1994. FASEB J. 8, 529.
          Rasschaert, J., et al. 1992. Endocrinology 130, 3522.
          Bennett, R.A. and Pegg, A.E. 1981. Cancer Res. 41, 2786.
          Yamamoto, H., et al. 1981. Nature 294, 284.
          Product Information
          CAS number18883-66-4
          FormOff-white to pale yellow crystalline solid
          Hill FormulaC₈H₁₅N₃O₇
          Chemical formulaC₈H₁₅N₃O₇
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Purity≥95% by HPLC
          Physicochemical Information
          ContaminantsHeavy metals: ≤5 ppm
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSLZ5775000
          Safety Information
          R PhraseR: 20/21/22-45-46-61

          Harmful by inhalation, in contact with skin and if swallowed.
          May cause cancer.
          May cause heritable genetic damage.
          May cause harm to the unborn child.
          S PhraseS: 22-36/37/39-45

          Do not breathe dust.
          Wear suitable protective clothing, gloves and eye/face protection.
          In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Harmful & Carcinogenic / Teratogenic
          Storage -20°C
          Do not freeze Ok to freeze
          Special InstructionsUnstable in solution; reconstitute just prior to use. Following initial thaw, aliquot and freeze (-20°C).
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Streptozotocin - CAS 18883-66-4 - Calbiochem SDS

          Title

          Safety Data Sheet (SDS) 

          Streptozotocin - CAS 18883-66-4 - Calbiochem Certificates of Analysis

          TitleLot Number
          572201

          References

          Reference overview
          Kroncke, K.D., et al. 1995. Biol. Chem. Hoppe Seyler 376, 179.
          Kwon, N.S., et al. 1994. FASEB J. 8, 529.
          Rasschaert, J., et al. 1992. Endocrinology 130, 3522.
          Bennett, R.A. and Pegg, A.E. 1981. Cancer Res. 41, 2786.
          Yamamoto, H., et al. 1981. Nature 294, 284.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision24-September-2010 JSW
          Synonyms2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose
          DescriptionAn N-nitroso-containing compound that acts as a nitric oxide donor in pancreatic islets. An antibiotic effective against gram-negative bacteria. Causes DNA alkylation and DNA strand breaks in pancreatic islet cells. A diabetogenic agent.
          FormOff-white to pale yellow crystalline solid
          CAS number18883-66-4
          RTECSLZ5775000
          Chemical formulaC₈H₁₅N₃O₇
          Structure formulaStructure formula
          Purity≥95% by HPLC
          ContaminantsHeavy metals: ≤5 ppm
          SolubilityH₂O
          Storage -20°C
          Do Not Freeze Ok to freeze
          Special InstructionsUnstable in solution; reconstitute just prior to use. Following initial thaw, aliquot and freeze (-20°C).
          Toxicity Harmful & Carcinogenic / Teratogenic
          Merck USA index14, 8832
          ReferencesKroncke, K.D., et al. 1995. Biol. Chem. Hoppe Seyler 376, 179.
          Kwon, N.S., et al. 1994. FASEB J. 8, 529.
          Rasschaert, J., et al. 1992. Endocrinology 130, 3522.
          Bennett, R.A. and Pegg, A.E. 1981. Cancer Res. 41, 2786.
          Yamamoto, H., et al. 1981. Nature 294, 284.