504983 S18986 - CAS 175340-20-2 - Calbiochem

S18986 - CAS 175340-20-2 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (S)-2,3-dihydro-[3,4]cyclopentano-1,2,4-benzothiadiazine-1,1-dioxide, (S)-2,3,3a,4-tetrahydro-1H-benzo[e]pyrrolo[2,1-c][1,2,4]thiadiazine 5,5-dioxide, AMPA Receptor Positive Allosteric Modulator, S18986

Primary Target: AMPA
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₀H₁₂N₂O₂S 175340-20-2

      Pricing & Availability

      Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
      5.04983.0001
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          		 Glass bottle 5 mg
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          Description
          OverviewA positive allosteric modulator selective for the AMPA receptors. A nootropic and neuroprotective agents frequently used in researches studying cognition, memory, and aging related cognitive declines. Induces production of BNDF and AMPA-mediated release of noradrenaline and acetylcholine. Biologically viable admitted systematically.
          Catalogue Number504983
          Brand Family Calbiochem®
          Synonyms(S)-2,3-dihydro-[3,4]cyclopentano-1,2,4-benzothiadiazine-1,1-dioxide, (S)-2,3,3a,4-tetrahydro-1H-benzo[e]pyrrolo[2,1-c][1,2,4]thiadiazine 5,5-dioxide, AMPA Receptor Positive Allosteric Modulator, S18986
          References
          ReferencesGupta, K., et al. 2009. Cell Death & Differentiation. 16, 624.
          Marighetto, A., et al. 2008. Beh. Pharmacol. 19, 235.
          Bloss, B., et al. 2008. Exp. Neurol. 210, 109.
          Lockhart, P., et al. 2007. Eur. J. Pharmacol. 561, 23.
          Munoz, C., et al. 2004. Neurobiol. Aging. 25, S224.
          Rosi, S., et al. 2004. Neurosci. Lett. 361, 120.
          Lebrun, C., et al. 2000. Eur. J. Pharmacol. 401, 205.
          Lockhart, B., et al. 2000. Eur. J. Pharmacol. 401, 145.
          Product Information
          CAS number175340-20-2
          FormWhite solid
          Hill FormulaC₁₀H₁₂N₂O₂S
          Chemical formulaC₁₀H₁₂N₂O₂S
          ReversibleY
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetAMPA
          Purity≥97% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          S18986 - CAS 175340-20-2 - Calbiochem SDS

          Title

          Safety Data Sheet (SDS) 

          References

          Reference overview
          Gupta, K., et al. 2009. Cell Death & Differentiation. 16, 624.
          Marighetto, A., et al. 2008. Beh. Pharmacol. 19, 235.
          Bloss, B., et al. 2008. Exp. Neurol. 210, 109.
          Lockhart, P., et al. 2007. Eur. J. Pharmacol. 561, 23.
          Munoz, C., et al. 2004. Neurobiol. Aging. 25, S224.
          Rosi, S., et al. 2004. Neurosci. Lett. 361, 120.
          Lebrun, C., et al. 2000. Eur. J. Pharmacol. 401, 205.
          Lockhart, B., et al. 2000. Eur. J. Pharmacol. 401, 145.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision17-July-2013 JSW
          Synonyms(S)-2,3-dihydro-[3,4]cyclopentano-1,2,4-benzothiadiazine-1,1-dioxide, (S)-2,3,3a,4-tetrahydro-1H-benzo[e]pyrrolo[2,1-c][1,2,4]thiadiazine 5,5-dioxide, AMPA Receptor Positive Allosteric Modulator, S18986
          DescriptionA positive allosteric modulator selective for the AMPA receptors. A nootropic and neuroprotective agents frequently used in researches studying cognition, memory, and aging related cognitive declines. Induces production of BNDF and AMPA-mediated release of noradrenaline and acetylcholine. Biologically viable admitted systematically.
          FormWhite solid
          CAS number175340-20-2
          Chemical formulaC₁₀H₁₂N₂O₂S
          Structure formulaStructure formula
          Purity≥97% by HPLC
          SolubilityDMSO (100 mM)
          Storage +2°C to +8°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesGupta, K., et al. 2009. Cell Death & Differentiation. 16, 624.
          Marighetto, A., et al. 2008. Beh. Pharmacol. 19, 235.
          Bloss, B., et al. 2008. Exp. Neurol. 210, 109.
          Lockhart, P., et al. 2007. Eur. J. Pharmacol. 561, 23.
          Munoz, C., et al. 2004. Neurobiol. Aging. 25, S224.
          Rosi, S., et al. 2004. Neurosci. Lett. 361, 120.
          Lebrun, C., et al. 2000. Eur. J. Pharmacol. 401, 205.
          Lockhart, B., et al. 2000. Eur. J. Pharmacol. 401, 145.