505877 (S)-(-)-Raclopride - CAS 84225-95-6 - Calbiochem

505877
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Key Specifications Table

Empirical FormulaCAS #
C₁₅H₂₀Cl₂N₂O₃ 84225-95-6

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      Glass bottle 10 mg
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      Description
      OverviewD2-like dopamine receptor antagonist targeting D2R (pKi =8.0), D3R (pKi = 7.9), and 5-HT1A R (pKi=5.2). Used to explore D2 like receptor mediated effects in neuropathic pain, and in antagonism studies of DA receptors during heroin usage and cocaine. D2 Receptor selectivity in various preps shows IC50 values around 32 nM.
      Catalogue Number505877
      Brand Family Calbiochem®
      SynonymsDopamine Receptor D2 Antagonist, (S)-Raclopride, Raclopride
      References
      ReferencesDang, Y. H. et al. 2010. Neurosci. 169, 1872.
      Platt, D. M. et al. 2010. J. Pharmacol. Exp. Ther. 332, 985.
      Product Information
      CAS number84225-95-6
      FormOff-white solid
      Hill FormulaC₁₅H₂₀Cl₂N₂O₃
      Chemical formulaC₁₅H₂₀Cl₂N₂O₃
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetD₂
      Purity≥99% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      (S)-(-)-Raclopride - CAS 84225-95-6 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Dang, Y. H. et al. 2010. Neurosci. 169, 1872.
      Platt, D. M. et al. 2010. J. Pharmacol. Exp. Ther. 332, 985.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision12-September-2013 JSW
      SynonymsDopamine Receptor D2 Antagonist, (S)-Raclopride, Raclopride
      DescriptionD2-like dopamine receptor antagonist targeting D2R (pKi =8.0), D3R (pKi = 7.9), and 5-HT1A R (pKi=5.2). Used to explore D2 like receptor mediated effects in neuropathic pain, and in antagonism studies of DA receptors during heroin usage and cocaine. D2 Receptor selectivity in various preps shows IC50 values around 32 nM.
      FormOff-white solid
      CAS number84225-95-6
      Chemical formulaC₁₅H₂₀Cl₂N₂O₃
      Structure formulaStructure formula
      Purity≥99% by HPLC
      SolubilityDMSO (100 mM) or Ethanol (25 mM)
      Storage +2°C to +8°C
      Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesDang, Y. H. et al. 2010. Neurosci. 169, 1872.
      Platt, D. M. et al. 2010. J. Pharmacol. Exp. Ther. 332, 985.