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506130 Reserpine - CAS 50-55-5 - Calbiochem

Reserpine - CAS 50-55-5 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: VMAT2 Inhibitor, Reserpine, Vesicular monoamine transporter (VMAT) Antagonist, Reserpine

Primary Target: VMAT2
506130
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Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
50-55-5C₃₃H₄₀N₂O₉

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      		 Glass bottle 250 mg
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      Description
      OverviewBinds the vesicular monoamine transporter (VMAT2) and acts as an irreversible transport inhibitor of biogenic amines. Used as a long-lasting bioamine depleter. Prevents bioamine transport into synaptic vesicles and chromaffin granules. Used as antihypertensive and antipsychotic drugs.
      Catalogue Number506130
      Brand Family Calbiochem®
      SynonymsVMAT2 Inhibitor, Reserpine, Vesicular monoamine transporter (VMAT) Antagonist, Reserpine
      References
      ReferencesOe, T., et al. 2010. Neurosci. 169, 1860.
      Metzger, R. et al. 2002. Eur. J. Pharmacol. 456, 39.
      Heslop, E., et al. 1999. Neuropharmacol. 38, 883.
      Schuldiner, S., et al. 1993. J. Biol. Chem. 268, 29.
      Product Information
      CAS number50-55-5
      FormOff-white solid
      Hill FormulaC₃₃H₄₀N₂O₉
      Chemical formulaC₃₃H₄₀N₂O₉
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetVMAT2
      Purity≥98% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 22

      Harmful if swallowed.
      S PhraseS: 46

      If swallowed, seek medical advice immediately and show this container or label.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Harmful & Carcinogenic / Teratogenic
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Reserpine - CAS 50-55-5 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Oe, T., et al. 2010. Neurosci. 169, 1860.
      Metzger, R. et al. 2002. Eur. J. Pharmacol. 456, 39.
      Heslop, E., et al. 1999. Neuropharmacol. 38, 883.
      Schuldiner, S., et al. 1993. J. Biol. Chem. 268, 29.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision15-November-2013 JSW
      SynonymsVMAT2 Inhibitor, Reserpine, Vesicular monoamine transporter (VMAT) Antagonist, Reserpine
      DescriptionBinds the vesicular monoamine transporter (VMAT2) and acts as an irreversible transport inhibitor of biogenic amines. Used as a long-lasting bioamine depleter. Prevents bioamine transport into synaptic vesicles and chromaffin granules. Used as antihypertensive and antipsychotic drugs.
      FormOff-white solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number50-55-5
      Chemical formulaC₃₃H₄₀N₂O₉
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMSO (100 mM)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Harmful & Carcinogenic / Teratogenic
      ReferencesOe, T., et al. 2010. Neurosci. 169, 1860.
      Metzger, R. et al. 2002. Eur. J. Pharmacol. 456, 39.
      Heslop, E., et al. 1999. Neuropharmacol. 38, 883.
      Schuldiner, S., et al. 1993. J. Biol. Chem. 268, 29.