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SCC007 ReNcell® CX Human Neural Progenitor Cell Line

1 ea  
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      Key Specifications Table

      Key Applications
      Catalogue NumberSCC007
      Brand Family Chemicon®
      Trade Name
      • ReNcell
      • Chemicon
      DescriptionReNcell® CX Human Neural Progenitor Cell Line
      OverviewReNcell® CX is an immortalized human neural progenitor cell line with the ability to readily differentiate into neurons and glial cells. ReNcell® CX was derived from the cortical region of human fetal brain. Immortalized by retroviral transduction with the c-myc oncogene, this cell line grows rapidly as a monolayer on laminin with a doubling time of 20-30 hours. Karyotype analyses indicate that the ReNcell® CX retains a normal diploid karyotype in culture even after prolonged passage (>45 passages). ReNcell® CX was developed by the ReNeuron Group plc, a biotech company that specializes in using human somatic stem cells for therapeutics. ReNcell® CX may be used for a variety of research applications such as studies of neurotoxicity, neurogenesis, electrophysiology, neurotransmitter and receptor functions. ReNcell® CX cells have been obtained in a legal and ethical manner, compliant with current local informed consent procedures.

      ReNcell Now Used in a 3D Cell Model of Alzheimer's Disease!
      Tanzi, R and Kim, DY et. al. A three-dimensional human neural cell culture model of Alzheimer's disease. Nature. 2014 Nov 13;515(7526):274-8.
      (Published in Nature)
      Materials Required but Not Delivered1. ReNcell® NSC Maintenance Medium (Millipore Cat. No. SCM005)
      2. ReNcell® NSC Freezing Medium (Millipore Cat. No. SCM007)
      3. Basic fibroblast growth factor (bFGF; FGF-2; Specific Activity > 2 X 106 Units/mg. Millipore Cat. No. GF003)
      4. Epidermal growth factor (EGF; Specific Activity > 1 x 107 Units/mg; Millipore Cat. No. GF001)
      5. Laminin (Millipore Cat. No. CC095)
      6. DMEM/F12 w/o HEPES, w/ L-Glutamine (Millipore Cat. No. DF-042-B)
      7. Accutase (Millipore Cat. No. SCR005)
      8. Tissue culture-ware
      9. Phosphate-Buffered Saline (1X PBS) (Millipore Cat. No. BSS-1005-B)
      10. Fixative (e.g. 4% Paraformaldehyde in 1X PBS)
      11. Blocking Solution (5% normal donkey serum, 0.3% Triton X-100 in 1X PBS)
      12. Primary and secondary antibodies 13.4'-6-Diamidino-2-phenylindole (DAPI) / PBS Solution
      14. Anti-fading mounting solution (DABCO/PVA)
      15. Hemacytometer
      16. Microscope
      Product Information
      • > 1x106 viable ReNcell® CX cells
      Quality LevelMQ100
      ApplicationReNcell® CX is an immortalized human neural progenitor cell line with the ability to readily differentiate into neurons & glial cells.
      Key Applications
      • Stem Cell Culture
      Biological Information
      SourceHuman cortical brain tissue
      Stem Cell Type
      • Neural Stem Cells
      Cell Line Type
      • Neural Stem Cells
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEach lot of ReNcell® CX cells has been validated for high level of expression of Nestin and Sox 2 and for their self-renewal and multi-lineage differentiation capacities (please refer to datasheet figures). Cells also display normal karyotype as assessed by chromosome spread and tested negative for mycoplasma. Maternal blood has been screened for HIV, HTLV, Hepatitis B and C.
      Usage Statement
      • This product contains genetically modified organisms (GMO). Within the EU GMOs are regulated by Directives 2001/18/EC and 2009/41/EC of the European Parliament and of the Council and their national implementation in the member States respectively. This legislation obliges MilliporeSigma to request certain information about you and the establishment where the GMOs are being handled. Click here for Enduser Declaration (EUD) Form.
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsWhen stored at the recommended storage conditions (liquid nitrogen), ReNcell® CX cells are stable up to the expiration date. Do not expose to elevated temperatures. Discard any remaining reagents after the expiration date. We recommend that the cells be used within ten passages.
      Packaging Information
      Material Size1 ea
      Transport Information
      Supplemental Information


      ReNcell® CX Human Neural Progenitor Cell Line SDS


      Safety Data Sheet (SDS) 


      Reference overviewApplicationPub Med ID
      Differential development of neuronal physiological responsiveness in two human neural stem cell lines.
      Donato, R; Miljan, EA; Hines, SJ; Aouabdi, S; Pollock, K; Patel, S; Edwards, FA; Sinden, JD
      BMC neuroscience  8  36  2007

      Show Abstract
      Immunocytochemistry17531091 17531091

      Technical Info

      ReNcell VM Cell Line - A Model of Human Neural Development and Differentiation

      Data Sheet

      ReNcell™ CX Human Neural Progenitor Cell Line

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      Life Science Research > Cell Culture and Systems > Cell Lines > Stem Cell Lines