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Description
Overview
A selective agonist of GABAB receptors that is shown to activate K+ conductance in hippocampal neurons. Also acts as an antispastic agent and a skeletal muscle relaxant. It is also an experimental drug to treat autism.
Catalogue Number
505873
Brand Family
Calbiochem®
Synonyms
STX 209, GABAB Agonist, Baclofen, Arbaclofen
References
References
Sodickson, D.L., et al., 1996. J. Neurosci.16, 6374. Ahuja, S. et al., 1985. Analytical Profile of Drug Substances14, 527.
If swallowed, seek medical advice immediately and show this container or label.
Product Usage Statements
Storage and Shipping Information
Ship Code
Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity
Toxic
Hazardous Materials Attention:
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage
+2°C to +8°C
Protect from Light
Protect from light
Do not freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 3 months at -20°C.
Sodickson, D.L., et al., 1996. J. Neurosci.16, 6374. Ahuja, S. et al., 1985. Analytical Profile of Drug Substances14, 527.
Data Sheet
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
20-September-2013 JSW
Synonyms
STX 209, GABAB Agonist, Baclofen, Arbaclofen
Description
A selective agonist of GABAB receptors that is shown to activate K+ conductance in hippocampal neurons. Also acts as an antispastic agent and a skeletal muscle relaxant. It is also an experimental drug to treat autism.
Form
Off-white solid
CAS number
69308-37-8
Chemical formula
C₁₀H₁₂ClNO₂
Structure formula
Purity
≥98% by Chiral HPLC
Solubility
H₂O
Storage
Protect from light
+2°C to +8°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 3 months at -20°C.
Toxicity
Toxic
References
Sodickson, D.L., et al., 1996. J. Neurosci.16, 6374. Ahuja, S. et al., 1985. Analytical Profile of Drug Substances14, 527.