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504631 Quisqualic acid - CAS 52809-07-1 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: β-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine, 3-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine

Primary Target: Group II and III mGlu receptors
504631
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Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
52809-07-1C₅H₇N₃O₅

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      Description
      OverviewA potent agonist highly selective for group I (EC50 ≤3 µM) over group II and III mGlu receptors (EC50 >40 µM) and a potent agonist of AMPA receptors. Often used for inducing excitotoxic lesions of basal forebrain cholinergic neurons and spinal neurons.
      Catalogue Number504631
      Brand Family Calbiochem®
      Synonymsβ-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine, 3-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine
      References
      ReferencesJin, R., et al. 2012. Biochemistry. 41, 15635.
      Kuang, D., et al. 2006. Biochem. & Biophys. Res. Comm. 345, 1.
      Zhang, W., et al. 2006. Biophysical J. 91, 1336.
      Muir, J., et al. 1993. Behav. Brain Res. 57, 123.
      Product Information
      CAS number52809-07-1
      FormWhite powder
      Hill FormulaC₅H₇N₃O₅
      Chemical formulaC₅H₇N₃O₅
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Target Group II and III mGlu receptors
      Purity≥98% by TLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Quisqualic acid - CAS 52809-07-1 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Jin, R., et al. 2012. Biochemistry. 41, 15635.
      Kuang, D., et al. 2006. Biochem. & Biophys. Res. Comm. 345, 1.
      Zhang, W., et al. 2006. Biophysical J. 91, 1336.
      Muir, J., et al. 1993. Behav. Brain Res. 57, 123.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision28-June-2013 JSW
      Synonymsβ-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine, 3-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine
      DescriptionA potent agonist highly selective for group I (EC50 ≤3 µM) over group II and III mGlu receptors (EC50 >40 µM) and a potent agonist of AMPA receptors. Often used for inducing excitotoxic lesions of basal forebrain cholinergic neurons and spinal neurons.
      FormWhite powder
      CAS number52809-07-1
      Chemical formulaC₅H₇N₃O₅
      Structure formulaStructure formula
      Purity≥98% by TLC
      SolubilityH₂O (0.5 mg/ml), 1M NH₄OH (20 mg/ml) or 0.1M HCl (1.4 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesJin, R., et al. 2012. Biochemistry. 41, 15635.
      Kuang, D., et al. 2006. Biochem. & Biophys. Res. Comm. 345, 1.
      Zhang, W., et al. 2006. Biophysical J. 91, 1336.
      Muir, J., et al. 1993. Behav. Brain Res. 57, 123.