Product Information
Applications
Biological Information
Purity≥98% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications

Documentation

PPARβ/δ Antagonist, PT-S58 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

PPARβ/δ Antagonist, PT-S58 - Calbiochem Certificates of Analysis

TitleLot Number
516569

References

Reference overview
Naruhn, S., et al. 2011, Mol. Pharm. 80, 828.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision18-May-2012 JSW
SynonymsPPARβ Antagonist II, methyl 3-(N-(4-(tert-butylamino)-2-methoxyphenyl)sulfamoyl)thiophene-2-carboxylate, PPARδ Antagonist II
DescriptionA cell-permeable, diaryl sulfonamide PPARβ/δ subtype-specific pure competitive antagonist with an IC50 of 98 nM. Antagonizes ligand binding without enabling coregulator interactions. Inhibits the PPARβ/δ specific agonist-induced transcriptional activity in cell cultures.
FormDark yellow solid
Intert gas (Yes/No) Packaged under inert gas
Chemical formulaC₁₇H₂₂N₂O₅S₂
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityDMSO (100 mg/ml; clear, amber-yellow solution)
Storage -20°C
Protect from light
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesNaruhn, S., et al. 2011, Mol. Pharm. 80, 828.

Related Products & Applications

Categories

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Other Inhibitors of Biological Interest > Peroxisome Proliferator-Activated Receptor (PPAR) Inhibitors