Millipore Sigma Vibrant Logo

539610 PKCζ/ι Pseudosubstrate Inhibitor - Calbiochem

539610
View Pricing & Availability

Overview

Replacement Information

Key Specifications Table

Empirical Formula
C₇₆H₁₂₈N₃₀O₁₆

Pricing & Availability

Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
539610-500UG
Retrieving availability...
Limited AvailabilityLimited Availability
Stocked 
Discontinued
Limited Quantities Available
Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      Plastic ampoule 500 μg
      Retrieving price...
      Price could not be retrieved
      Minimum Quantity is a multiple of
      Maximum Quantity is
      Upon Order Completion More Information
      You Saved ()
       
      Request Pricing
      Description
      OverviewA selective, reversible, and substrate competitive inhibitor of protein kinase Cζ and protein kinase Cι (PKCζ/ι) isozymes.
      Catalogue Number539610
      Brand Family Calbiochem®
      SynonymsSIYRRGARRWRKL, Protein Kinase Cζ/ι Pseudosubstrate Inhibitor
      References
      ReferencesSajan, M.P., et al. 1999. J. Biol. Chem. 274, 30495.
      Laudanna, C., et al. 1998. J. Biol. Chem. 273, 30306.
      Standaert, M.L., et al. 1997. J. Biol. Chem. 272, 30075.
      Product Information
      ATP CompetitiveN
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₇₆H₁₂₈N₃₀O₁₆
      Chemical formulaC₇₆H₁₂₈N₃₀O₁₆
      Hygroscopic Hygroscopic
      ReversibleY
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetPKCζ
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Peptide SequenceH-Ser-Ile-Tyr-Arg-Arg-Gly-Ala-Arg-Arg-Trp-Arg-Lys-Leu-OH
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      PKCζ/ι Pseudosubstrate Inhibitor - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      PKCζ/ι Pseudosubstrate Inhibitor - Calbiochem Certificates of Analysis

      TitleLot Number
      539610

      References

      Reference overview
      Sajan, M.P., et al. 1999. J. Biol. Chem. 274, 30495.
      Laudanna, C., et al. 1998. J. Biol. Chem. 273, 30306.
      Standaert, M.L., et al. 1997. J. Biol. Chem. 272, 30075.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision11-January-2010 RFH
      SynonymsSIYRRGARRWRKL, Protein Kinase Cζ/ι Pseudosubstrate Inhibitor
      DescriptionNon-cell-permeable protein kinase Cζ and protein kinase Cι pseudosubstrate sequence peptide that can be used as a selective, reversible, and substrate competitive inhibitor PKCζ/ι in in vitro kinase assays.
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      Recommended reaction conditions
      PKCζ or PKCι -containing sample is incubated at 30-37°C, with or without 400 µM PKCζ/ι pseudosubstrate inhibitor, in 50 mM Tris-HCl buffer (pH 7.5) containing 5 mM MgCl2, 100 µM Na3VO4, 100 µM Na4P2O7, 1 mM NaF, 100 µM PMSF, 50 µM ATP, 5 µCi [γ-32P]ATP, 4 µg phosphatidylserine, and 40 µM PKCζ/ι substrate (Cat. No. 539667).
      Chemical formulaC₇₆H₁₂₈N₃₀O₁₆
      Peptide SequenceH-Ser-Ile-Tyr-Arg-Arg-Gly-Ala-Arg-Arg-Trp-Arg-Lys-Leu-OH
      Purity≥95% by HPLC
      SolubilityGlacial acetic acid (2 mg/ml) or H₂O (2 mg/ml)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesSajan, M.P., et al. 1999. J. Biol. Chem. 274, 30495.
      Laudanna, C., et al. 1998. J. Biol. Chem. 273, 30306.
      Standaert, M.L., et al. 1997. J. Biol. Chem. 272, 30075.