Millipore Sigma Vibrant Logo

124505 Osmium(VIII) oxide

View Pricing & Availability


Replacement Information
Replacement InformationIn North America 124505.0001 replaces OX0260-5, material is similar, pack size is same
In North America 124505.0500 replaces OX0260-3, material is similar, pack size is same

Pricing & Availability

Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
Retrieving availability...
Limited AvailabilityLimited Availability
Limited Quantities Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      Glass ampoule 500 mg
      Retrieving price...
      Price could not be retrieved
      Minimum Quantity is a multiple of
      Maximum Quantity is
      Upon Order Completion More Information
      You Saved ()
      Request Pricing
      Catalogue Number124505
      ReplacesOX0260-5; OX0260-3
      SynonymsOsmic acid, Osmiumtetraoxide
      DescriptionOsmium(VIII) oxide
      OverviewOsmium tetroxide for microscopy can be used to visualize unsaturated lipids. A part of the lipids is immediately blackened by the influence of osmic acid solution. The immediate black coloration results from the -C=C- double bond of the unsaturated fatty acid. The fatty acids that are made brownish at first can be blackened by treatment with 60-70% alcohol. For electron microscopy or semithin sectioning the glutardialdehyde-fixed specimens are post-fixed with osmium(VIII) oxide. Lipid inclusions appear black on a yellow to brown background. It is an IVD / CE registered product. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.
      Product Information
      CAS number20816-12-0
      EC index number076-001-00-5
      EC number244-058-7
      Hill FormulaO₄Os
      Chemical formulaOsO₄
      Molar Mass254.19 g/mol
      Quality LevelMQ400
      Applicationfor microscopy
      Biological Information
      Physicochemical Information
      Boiling point130 °C (1013 hPa)
      Density4.91 g/cm3 (20 °C)
      Melting Point40 °C
      pH value6 (25 g/l, H₂O, 20 °C)
      Vapor pressure10 hPa (20 °C)
      Bulk density1500 kg/m3
      Solubility65 g/l
      Materials Information
      Toxicological Information
      LD 50 oralLD50 Rat 15 mg/kg
      Safety Information according to GHS
      Hazard Pictogram(s) Hazard Pictogram(s)
      Hazard Pictogram(s)
      Hazard Statement(s)H300 + H310 + H330: Fatal if swallowed, in contact with skin or if inhaled.
      H314: Causes severe skin burns and eye damage.
      Precautionary Statement(s)P260: Do not breathe dust/ fume/ gas/ mist/ vapours/ spray.
      P270: Do not eat, drink or smoke when using this product.
      P280: Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection.
      P303 + P361 + P353: IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water.
      P304 + P340 + P310: IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor.
      P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
      Signal WordDanger
      Storage class6.1A Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
      WGKWGK 1 slightly hazardous to water
      Residues containing valuable recoverable metals should be forwarded for recycling. Container H.
      Safety Information
      Categories of dangervery toxic, corrosive
      Product Usage Statements
      Storage and Shipping Information
      StorageStore at +15°C to +25°C.
      Packaging Information
      Transport Information
      Declaration (railroad and road) ADR, RIDUN 2471 , 6.1, I
      Declaration (transport by air) IATA-DGRUN 2471 , 6.1, I
      Declaration (transport by sea) IMDG-CodeUN 2471 , 6.1, I, Marine Pollutant: P
      Supplemental Information
      Identity (Raman-spectrum)conforms

      Related Products & Applications

      Accessories (Primary)

      Catalog Number Description  
      112179 Glutardialdehyde solution 25% Show Pricing & Availability

      Related Products By: Application Facete


      IVD/OEM Materials & Reagents > Microscopy > Histology > Histological Staining Solutions
      IVD/OEM Materials & Reagents > Microscopy > Histology > Histological Staining Kits
      IVD/OEM Materials & Reagents
      IVD/OEM Materials & Reagents > Microscopy > Universal Reagents > Fixation