496260 Oncostatin M, Human, Recombinant, E. coli

496260
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496260-10UG
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      Plastic ampoule 10 μg
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      Description
      OverviewRecombinant, human oncostatin M expressed in E. coli. Pleiotropic cytokine which inhibits growth of A375 melanoma cells and mouse M1 myeloid leukemic cells. Enhances the growth of both endothelial and hematopoietic cells. Has also been reported to have growth stimulatory activities on normal fibroblasts, AIDS-Kaposis sarcoma cells, and a human erythroleukemic cell line, TF-1.
      Catalogue Number496260
      Brand Family Calbiochem®
      SynonymsrhOSM
      References
      ReferencesBoileau, C., et al. 2000. J. Immunol. 164, 5713.
      Miyajima, A., et al. 2000. Cytokine Growth Factor Rev. 11, 177.
      Linsley, P.S., et al. 1990. Mol. Cell. Biol. 10, 1882.
      Kitamura, T., et al. 1989. J. Cell Physiol. 140, 323.
      Product Information
      CAS number106956-32-5
      FormLyophilized
      FormulationLyophilized from sterile-filtered 30% acetonitrile, 0.1% TFA, 50 µg BSA/µg rhOSM.
      Quality LevelMQ100
      Applications
      Biological Information
      Biological activityED₅₀ = 0.15-0.30 ng/ml as measured in a cell proliferation assay using a factor-dependent human erythroleukemic cell line, TF-1
      Purity≥97% by SDS-PAGE
      Physicochemical Information
      ContaminantsEndotoxin: ≤1 EU/µg rhOSM
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Avoid freeze/thaw cycles of solutions. Stock solutions are stable for up to 3 months at -70°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Oncostatin M, Human, Recombinant, E. coli SDS

      Title

      Safety Data Sheet (SDS) 

      Oncostatin M, Human, Recombinant, E. coli Certificates of Analysis

      TitleLot Number
      496260

      References

      Reference overview
      Boileau, C., et al. 2000. J. Immunol. 164, 5713.
      Miyajima, A., et al. 2000. Cytokine Growth Factor Rev. 11, 177.
      Linsley, P.S., et al. 1990. Mol. Cell. Biol. 10, 1882.
      Kitamura, T., et al. 1989. J. Cell Physiol. 140, 323.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision13-August-2008 RFH
      SynonymsrhOSM
      DescriptionRecombinant, human oncostatin M expressed in E. coli. Pleiotropic cytokine which inhibits growth of A375 melanoma cells and mouse M1 myeloid leukemic cells. Has also been reported to have growth stimulatory activities on normal fibroblasts, AIDS-Kaposi's sarcoma cells, and human erythroleukemia cell line, TF-1.
      FormLyophilized
      FormulationLyophilized from sterile-filtered 30% acetonitrile, 0.1% TFA, 50 µg BSA/µg rhOSM.
      CAS number106956-32-5
      Purity≥97% by SDS-PAGE
      ContaminantsEndotoxin: ≤1 EU/µg rhOSM
      Biological activityED₅₀ = 0.15-0.30 ng/ml as measured in a cell proliferation assay using a factor-dependent human erythroleukemic cell line, TF-1
      SolubilityReconstitute to a final concentration of ≥10 µg/ml in sterile PBS containing ≥0.1% BSA or HSA.
      Storage ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Avoid freeze/thaw cycles of solutions. Stock solutions are stable for up to 3 months at -70°C.
      Toxicity Standard Handling
      ReferencesBoileau, C., et al. 2000. J. Immunol. 164, 5713.
      Miyajima, A., et al. 2000. Cytokine Growth Factor Rev. 11, 177.
      Linsley, P.S., et al. 1990. Mol. Cell. Biol. 10, 1882.
      Kitamura, T., et al. 1989. J. Cell Physiol. 140, 323.