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100202 N,N-Dimethylformamide

100202
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Overview

Replacement Information

Key Specifications Table

CAS #EC NumberHill FormulaChemical FormulaMolar Mass
68-12-2 200-679-5 C₃H₇NO HCON(CH₃)₂ 73.09 g/mol

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              Description
              Catalogue Number100202
              SynonymsDMF, N,N-Dimethylmethanamide, Formic acid dimethylamide
              DescriptionN,N-Dimethylformamide
              OverviewSupraSolv® solvents for headspace gas chromatography are developed particularly for the analysis of residual solvents in drug substances, excipients and drug products according to ICH, Ph Eur and USP - SupraSolv® headspace solvents are tested for all residual solvents defined by the ICH.
              References
              Product Information
              CAS number68-12-2
              EC index number616-001-00-X
              EC number200-679-5
              Hill FormulaC₃H₇NO
              Chemical formulaHCON(CH₃)₂
              Molar Mass73.09 g/mol
              HS Code2924 19 00
              Structure formula ImageStructure formula Image
              Quality LevelMQ100
              Applications
              ApplicationN,N-Dimethylformamide for headspace gas chromatography SupraSolv®. CAS 68-12-2, EC Number 200-679-5, chemical formula HCON(CH₃)₂.
              Biological Information
              Physicochemical Information
              Boiling point153 °C (1013 hPa)
              Density0.94 g/cm3 (20 °C)
              Explosion limit2.2 - 16 %(V)
              Flash point57.5 °C
              Ignition temperature410 °C
              Melting Point-61 °C (External MSDS)
              pH value7 (200 g/l, H₂O, 20 °C)
              Vapor pressure3.77 hPa (20 °C)
              Solubility1000 g/l soluble
              Dimensions
              Materials Information
              Toxicological Information
              LD 50 oralLD50 Rat 3010 mg/kg
              LD 50 dermalLD50 Rabbit 1500 mg/kg
              Safety Information according to GHS
              Hazard Pictogram(s) Hazard Pictogram(s)
              Hazard Pictogram(s)
              Hazard Pictogram(s)
              Hazard Statement(s)H360D: May damage the unborn child.
              H226: Flammable liquid and vapour.
              H312 + H332: Harmful in contact with skin or if inhaled.
              H319: Causes serious eye irritation.
              Precautionary Statement(s)P201: Obtain special instructions before use.
              P210: Keep away from heat.
              P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
              P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
              P308 + P313: IF exposed or concerned: Get medical advice/ attention.
              Signal WordDanger
              RTECSLQ2100000
              Storage class3 Flammable liquids
              WGKWGK 2 obviously hazardous to water
              Disposal3
              Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
              Safety Information
              Hazard Symbols Hazard SymbolsToxic
              Categories of dangertoxic for reproduction, harmful, irritant
              R PhraseR 61-20/21-36
              May cause harm to the unborn child.Also harmful by inhalation and in contact with skin.Irritating to eyes.
              S PhraseS 53-45
              Avoid exposure - obtain special instructions before use.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
              Product Usage Statements
              Storage and Shipping Information
              StorageStore at +2°C to +30°C.
              Packaging Information
              Transport Information
              Declaration (railroad and road) ADR, RIDUN 2265 , 3, III
              Declaration (transport by air) IATA-DGRUN 2265 , 3, III
              Declaration (transport by sea) IMDG-CodeUN 2265 , 3, III
              Supplemental Information
              Specifications
              Purity (GC)≥ 99.8 %
              Identity (IR)conforms
              Evaporation residue≤ 3.0 mg/l
              Water≤ 0.05 %
              Color≤ 10 Hazen
              GC/HS (Every residual solvent of class 1 acc. ICH)≤ 1 µg/g
              GC/HS (Every residual solvent of class 2 acc. ICH)≤ 10 µg/g
              GC/HS (Every residual solvent of class 3 acc. ICH)≤ 50 µg/g
              Suitable as solvent for the analysis of residual solvents of ICH classes 1,2 and 3 according to Ph Eur und USP.
              Formic acid and acetic acid are not detected.

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              Categories

              Reagents, Chemicals and Labware > Solvents > Solvents for Instrumental Organic Analysis > Solvents for Headspace Gas Chromatography, SupraSolv®
              Analytics and Sample Preparation > Analytical Chromatography > Gas Chromatography GC > Solvents for Headspace Gas Chromatography, SupraSolv®