106425 N-Acetyl-L-cysteine - CAS 616-91-1 - Calbiochem

106425
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Overview

Replacement Information

Key Specifications Table

Empirical FormulaCAS #
C₅H₉NO₃S 616-91-1

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106425-5GM
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      Description
      OverviewMucolytic agent and thiol-based antioxidant that has a protective effect against oxygen free radicals in early septic shock. Increases cellular pools of free-radical scavengers. Inhibitor of HIV replication. May serve as a substrate for microsomal glutathione transferase. Induces apoptosis in human and rat smooth muscle cells.
      Catalogue Number106425
      Brand Family Calbiochem®
      SynonymsLNAC
      References
      ReferencesOrtolani, O., et al. 2000. Am. J. Respir. Crit. Care Med. 161, 1907.
      Tsai, J.C., et al. 1996. J. Biol. Chem. 271, 3667.
      Ferrari, G., et al. 1995. J. Neurosci. 15, 2857.
      Weinander, R., et al. 1994. J. Biol. Chem. 269, 71.
      Product Information
      CAS number616-91-1
      FormWhite solid
      Hill FormulaC₅H₉NO₃S
      Chemical formulaC₅H₉NO₃S
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥98% by titration
      Physicochemical Information
      ContaminantsFe: ≤20 ppm
      Cl: ≤ 0.04%
      Sulfate: ≤ 0.03%
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSHA1660000
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +15°C to +30°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Aqueous stock solutions are stable for up to 1 month at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      N-Acetyl-L-cysteine - CAS 616-91-1 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      N-Acetyl-L-cysteine - CAS 616-91-1 - Calbiochem Certificates of Analysis

      TitleLot Number
      106425

      References

      Reference overview
      Ortolani, O., et al. 2000. Am. J. Respir. Crit. Care Med. 161, 1907.
      Tsai, J.C., et al. 1996. J. Biol. Chem. 271, 3667.
      Ferrari, G., et al. 1995. J. Neurosci. 15, 2857.
      Weinander, R., et al. 1994. J. Biol. Chem. 269, 71.

      Citations

      Title
    • Teresa Sanchez Alcaraz, et al. (2004) Involvement of Glutathione as a Mechanism of Indirect Protection against Spontaneous Ex Vivo Apoptosis Associated with Bovine Leukemia Virus. Journal of Virology 78, 6180-6190.
    • Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision01-May-2017 JSW
      SynonymsLNAC
      DescriptionA mucolytic agent and thio-based antioxidant. Increases the cellular pool of free-radical scavengers. Inhibits HIV replication. Prevents apoptotic death of neuronal cells. Antidote for acetaminophen poisoning. May serve as a substrate for microsomal glutathione transferase. Induces apoptosis in human and rat smooth muscle cells.
      FormWhite solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number616-91-1
      RTECSHA1660000
      Chemical formulaC₅H₉NO₃S
      Structure formulaStructure formula
      Purity≥98% by titration
      ContaminantsFe: ≤20 ppm
      Cl: ≤ 0.04%
      Sulfate: ≤ 0.03%
      SolubilityH₂O (50 mg/ml)
      Storage +15°C to +30°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Aqueous stock solutions are stable for up to 1 month at -20°C.
      Toxicity Standard Handling
      Merck USA index14, 88
      ReferencesOrtolani, O., et al. 2000. Am. J. Respir. Crit. Care Med. 161, 1907.
      Tsai, J.C., et al. 1996. J. Biol. Chem. 271, 3667.
      Ferrari, G., et al. 1995. J. Neurosci. 15, 2857.
      Weinander, R., et al. 1994. J. Biol. Chem. 269, 71.
      Citation
    • Teresa Sanchez Alcaraz, et al. (2004) Involvement of Glutathione as a Mechanism of Indirect Protection against Spontaneous Ex Vivo Apoptosis Associated with Bovine Leukemia Virus. Journal of Virology 78, 6180-6190.