MAB2300 Milli-Mark™ Pan Neuronal Marker

100 µL  
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      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, R, M ICC, IHC, IF, IH(P) M Purified Monoclonal Antibody
      Catalogue NumberMAB2300
      Trade Name
      • Neuro-Chrom
      DescriptionMilli-Mark™ Pan Neuronal Marker
      Background InformationAntibodies to neuronal proteins have become critical tools for identifying neurons and discerning morphological characteristics in culture and complex tissue. While the labeling from classic histological techniques such as Golgi staining and modern molecular approaches such as GFP constructs yield excellent cytoarchitectural detail, these approaches are technically challenging and impractical for many neuroscience research needs. Neuron-specific antibodies are convenient precision tools useful in revealing cytoarchitecture, but are limited to the protein target distribution within the neuron, which may differ greatly from nucleus to soma to dendrite and axon. To achieve as complete a morphological staining as possible across all parts of neurons, Millipore has developed a monoclonal antibody blend that reacts against key somatic, nuclear, dendritic, and axonal proteins distributed across the pan-neuronal architecture that can then be detected by a single secondary antibody. This antibody cocktail has been validated in diverse fixations, cell culture and immunohistochemistry protocols, including archival brain tissue, giving researchers a convienent and specific qualitative and quantitative tool for studying neuronal morphology.
      Product Information
      • Rat E18 cortex primary neurons
      PresentationBlended monoclonal antibody cocktail in PBS with 0.05% NaN3
      Quality LevelMQ100
      ApplicationMilli-Mark Pan Neuronal Marker is an antibody targeting the Pan Neuronal Marker protein, validated for use in ICC, IHC, IF & IHC.
      Key Applications
      • Immunocytochemistry
      • Immunohistochemistry
      • Immunofluorescence
      • Immunohistochemistry (Paraffin)
      Biological Information
      EpitopeWhole Neuron Marker
      SpecificityCat. # MAB2300 is specific to axons (neurites), dendrites, nucleus, and the cell body of neurons.
      Species Reactivity
      • Human
      • Rat
      • Mouse
      Species Reactivity NoteRat, Mouse and Human. Reactivity with other species has not been determined.
      Antibody TypeMonoclonal Antibody
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely tested Rat E18 cortex primary neurons in Immunocytochemistry.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at 2-8°C for up to 1 year from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information


      Milli-Mark™ Pan Neuronal Marker SDS


      Safety Data Sheet (SDS) 

      Milli-Mark™ Pan Neuronal Marker Certificates of Analysis

      TitleLot Number
      Milli-Mark Pan Neuronal Marker - LV1578552LV1578552
      Milli-Mark Pan Neuronal Marker - NG1547603NG1547603
      Milli-Mark Pan Neuronal Marker - NG1630110NG1630110
      Milli-Mark Pan Neuronal Marker - NG1667751NG1667751
      Milli-Mark Pan Neuronal Marker - NG1726938NG1726938
      Milli-Mark Pan Neuronal Marker - NG1800801NG1800801
      Milli-Mark Pan Neuronal Marker - NG1849431NG1849431
      Milli-Mark Pan Neuronal Marker - NG1872056NG1872056
      Neuro-Chrom Pan Neuronal Marker - 20012522001252
      Neuro-Chrom Pan Neuronal Marker - 20519342051934


      Reference overviewApplicationSpeciesPub Med ID
      Prolonged morphine treatment alters δ opioid receptor post-internalization trafficking.
      Ong, EW; Xue, L; Olmstead, MC; Cahill, CM
      British journal of pharmacology  172  615-29  2015

      Show Abstract
      24819092 24819092
      Activation of developmental nuclear fibroblast growth factor receptor 1 signaling and neurogenesis in adult brain by α7 nicotinic receptor agonist.
      Narla, ST; Klejbor, I; Birkaya, B; Lee, YW; Morys, J; Stachowiak, EK; Prokop, D; Bencherif, M; Stachowiak, MK
      Stem cells translational medicine  2  776-88  2013

      Show Abstract
      ImmunofluorescenceMouse24014683 24014683
      Rod microglia: elongation, alignment, and coupling to form trains across the somatosensory cortex after experimental diffuse brain injury.
      Ziebell, JM; Taylor, SE; Cao, T; Harrison, JL; Lifshitz, J
      Journal of neuroinflammation  9  247  2012

      Show Abstract
      23111107 23111107
      The effects of vitamin D receptor silencing on the expression of LVSCC-A1C and LVSCC-A1D and the release of NGF in cortical neurons.
      Gezen-Ak, D; Dursun, E; Yilmazer, S
      PloS one  6  e17553  2011

      Show Abstract
      21408608 21408608
      Short-term fasting induces profound neuronal autophagy.
      Alirezaei, M; Kemball, CC; Flynn, CT; Wood, MR; Whitton, JL; Kiosses, WB
      Autophagy  6  702-10  2010

      Show Abstract Full Text Article
      20534972 20534972


      Enriched Neuronal Morphology Revealed By Monoclonal Cocktail Immunostaining

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