475882 Sigma-AldrichML-9, Hydrochloride - CAS 105637-50-1 - Calbiochem
A cell-permeable, reverisible and ATP-competitive inhibitor of myosin light chain kinase (Ki = 3.8 µM), protein kinase A (Ki = 32 µM), and protein kinase C (Ki = 54 µM).
More>> A cell-permeable, reverisible and ATP-competitive inhibitor of myosin light chain kinase (Ki = 3.8 µM), protein kinase A (Ki = 32 µM), and protein kinase C (Ki = 54 µM). Less<<Synonyms: 1-(5-Chloronaphthalene-1-sulfonyl)homopiperazine, HCl
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Overview
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Key Specifications Table
CAS # | Empirical Formula |
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105637-50-1 | C₁₅H₁₇ClN₂O₂S · HCl |
Pricing & Availability
Catalog Number | Availability | Packaging | Qty/Pack | Price | Quantity | |
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475882-1MG |
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Plastic ampoule | 1 mg |
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Product Information | |
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CAS number | 105637-50-1 |
ATP Competitive | Y |
Form | White solid |
Hill Formula | C₁₅H₁₇ClN₂O₂S · HCl |
Chemical formula | C₁₅H₁₇ClN₂O₂S · HCl |
Hygroscopic | Hygroscopic |
Reversible | Y |
Structure formula Image | |
Quality Level | MQ100 |
Applications |
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Biological Information | |
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Primary Target | Mlck |
Primary Target K<sub>i</sub> | 3.8 µM, 32 µM, 54 µM against myosin light chain kinase, protein kinase A, and protein kinase C, respectively |
Purity | ≥98% by TLC |
Physicochemical Information | |
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Cell permeable | Y |
Dimensions |
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Materials Information |
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Toxicological Information |
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Safety Information according to GHS |
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Safety Information |
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Product Usage Statements |
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Packaging Information |
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Supplemental Information |
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Specifications |
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Global Trade Item Number | |
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Catalog Number | GTIN |
475882-1MG | 04055977203509 |
Documentation
ML-9, Hydrochloride - CAS 105637-50-1 - Calbiochem SDS
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ML-9, Hydrochloride - CAS 105637-50-1 - Calbiochem Certificates of Analysis
Title | Lot Number |
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475882 |
References
Reference overview |
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Reig, J.A., et al. 1993. Neurochem. Res. 18, 317. Nagatsu, T., et al. 1987. Biochem. Biophys. Res. Commun. 143, 1045. Saitoh, M., et al. 1987. J. Biol. Chem. 262, 7796. Saitoh, M., et al. 1986. Biochem. Biophys. Res. Commun. 140, 280. |