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105020 L-Leucine

Overview

Replacement Information

Key Specifications Table

CAS #EC NumberHill FormulaMolar MassGrade Value
61-90-5 200-522-0 C₆H₁₃NO₂ 131.18 g/mol Ph Eur,USP

Pricing & Availability

Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
1050201000
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      Plastic bottle 1 kg
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      1050209010
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          Plastic drum 10 kg
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          Description
          Catalogue Number105020
          SynonymsLeu
          References
          Product Information
          CAS number61-90-5
          EC number200-522-0
          GradePh Eur,USP
          Hill FormulaC₆H₁₃NO₂
          Molar Mass131.18 g/mol
          HS Code2922 49 85
          Structure formula ImageStructure formula Image
          Quality LevelMQ500
          Applications
          Biological Information
          Physicochemical Information
          Density1.17 g/cm3 (20 °C)
          Melting Point270 - 340 °C (decomposition)
          pH value5.5 - 6.5 (20 g/l, H₂O, 20 °C)
          Vapor pressure<1 hPa (20 °C)
          Bulk density300 - 400 kg/m3
          Solubility18.9 g/l
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSOH2850000
          Storage class10 - 13 Other liquids and solids
          WGKWGK 1 slightly hazardous to water
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          StorageStore at +5°C to +30°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Assay (perchloric acid titration, calculated on dried substance)98.5 - 101.0 %
          Identity (IR-spectrum)passes test
          Identity (specific rotation)passes test
          Appearancewhite to almost white, crystalline powder or shiny flakes
          Appearance of solution (50 g/l; hydrochloric acid 1 mol/l)clear and not more intense in color than reference solution BY₆
          Spec. rotation (α 20/D, 40 g/l, hydrochloric acid 250 g/l, calc. on dried substance)+14.5 to +16.5
          Spec. rotation (α 25/D, 40 g/l, hydrochloric acid 6 mol/l, calc. on dried substance)+14.9 to +17.3
          pH (10 g/l, CO₂-free water)5.5 - 7.0
          Chloride (Cl)≤ 200 ppm
          Sulfate (SO₄)≤ 300 ppm
          Fe (Iron)≤ 10 ppm
          Related Compounds, total (TLC)≤ 0.5 %
          Related compounds (HPLC) (Isoleucine)≤ 0.8 %
          Related compounds (HPLC) (Any unspecified impurity)≤ 0.2 %
          Related compounds (HPLC) (Total unspecified impurities)≤ 1.0 %
          Ninhydrin-positive substances (LC) (impurity A (570 nm))≤ 0.8 %
          Ninhydrin-positive substances (LC) (any ninhydrin-positive impurity)≤ 0.2 %
          Ninhydrin-positive substances (LC) (ammonium (570 nm))≤ 0.02 %
          Ninhydrin-positive substances (LC) (total impurities)≤ 1.0 %
          Residual solvents (ICH Q3C)excluded by manufacturing process
          Sulfated ash (600 °C)≤ 0.1 %
          Loss on drying (105 °C; 3 h)≤ 0.2 %
          Bacterial endotoxins≤ 3.0 I.U./g
          Microbiological test (total aerobic microbial count (TAMC))≤ 100 CFU/g
          Microbiological test (total yeast and mould count (TYMC))≤ 100 CFU/g
          Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
          Corresponds to Ph. Eur., USP

          Documentation

          Material Qualification Dossier

          Title

          Quality Management Dossier

          Title

          Operational Excellence Dossier

          Title

          L-Leucine SDS

          Title

          Safety Data Sheet (SDS) 

          L-Leucine Certificates of Analysis

          Product Number PackagingSpecificationLot Number
          1050201000 Plastic bottlePDF Specification Document
          1050209010 Plastic drumPDF Specification Document

          Certificates

          Title