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420131 JNK Inhibitor III, Cell-Permeable, Negative Control - Calbiochem

The JNK Inhibitor III, Cell-Permeable, Negative Control controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: HIV-TAT₄₇₋₅₇-gaba-c-JUNδ₃₃₋₅₇, scrambled, Ac-YGRKKRRQRRR-gaba-DSNLIRGVLPTLMPKSLAQNKLKHA-NH₂

Primary Target: Serves as a negative control for JNK Inhibitor III, Cell-Permeable (Cat. No. 420130).
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420131
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Overview

Replacement Information

Key Specifications Table

Empirical Formula
C₁₉₁H₃₃₆N₇₀O₄₈S

Pricing & Availability

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420131-1MG
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      		 Plastic ampoule 1 mg
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      Description
      OverviewA cell-permeable 37-mer peptide that contains a scrambled human c-Jun δ domain (amino acids 33-57) sequence linked to that of HIV-TAT protein transduction domain (amino acids 47-57) via a γ-aminobutyric acid (GABA) spacer. Does not disrupt c-Jun/JNK complex formation and thus serves as a negative control for JNK Inhibitor III, Cell-Permeable (Cat. No. 420130).
      Catalogue Number420131
      Brand Family Calbiochem®
      SynonymsHIV-TAT₄₇₋₅₇-gaba-c-JUNδ₃₃₋₅₇, scrambled, Ac-YGRKKRRQRRR-gaba-DSNLIRGVLPTLMPKSLAQNKLKHA-NH₂
      References
      ReferencesHolzberg, D., et al. 2003. J. Biol. Chem. 278, 40213.
      Product Information
      ATP CompetitiveN
      FormLyophilized white solid
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₁₉₁H₃₃₆N₇₀O₄₈S
      Chemical formulaC₁₉₁H₃₃₆N₇₀O₄₈S
      Hygroscopic Hygroscopic
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetServes as a negative control for JNK Inhibitor III, Cell-Permeable (Cat. No. 420130).
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableY
      Peptide SequenceAc-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-gaba-Asp-Ser-Asn-Leu-Ile-Arg-Gly-Val-Leu-Pro-Thr-Leu-Met-Pro-Lys-Ser-Leu-Ala-Gln-Asn-Lys-Leu-Lys-His-Ala-NH₂
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      JNK Inhibitor III, Cell-Permeable, Negative Control - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      JNK Inhibitor III, Cell-Permeable, Negative Control - Calbiochem Certificates of Analysis

      TitleLot Number
      420131

      References

      Reference overview
      Holzberg, D., et al. 2003. J. Biol. Chem. 278, 40213.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision25-July-2008 RFH
      SynonymsHIV-TAT₄₇₋₅₇-gaba-c-JUNδ₃₃₋₅₇, scrambled, Ac-YGRKKRRQRRR-gaba-DSNLIRGVLPTLMPKSLAQNKLKHA-NH₂
      DescriptionA cell-permeable 37 amino acid peptide that contains a scrambled sequence derived from the JNK binding domain (δ) of human c-Jun (amino acids 33-57) fused to the HIV-TAT transduction domain (amino acids 47-57) via a γ-aminobutyric acid (GABA) spacer. Does not disrupt c-Jun/JNK complex formation. Serves as a negative control for JNK Inhibitor III, Cell-Permeable (Cat. No. 420130).
      FormLyophilized white solid
      FormulationSupplied as a trifluoroacetate salt.
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₁₉₁H₃₃₆N₇₀O₄₈S
      Peptide SequenceAc-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-gaba-Asp-Ser-Asn-Leu-Ile-Arg-Gly-Val-Leu-Pro-Thr-Leu-Met-Pro-Lys-Ser-Leu-Ala-Gln-Asn-Lys-Leu-Lys-His-Ala-NH₂
      Purity≥95% by HPLC
      SolubilityDMSO (1 mg/ml)
      Storage Protect from light
      -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesHolzberg, D., et al. 2003. J. Biol. Chem. 278, 40213.