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500528 InhibitorSelect™ TLR Signaling Pathway Panel - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Primary Target: Major hubs involved in TLR signaling cascade
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500528
  
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      Overview

      Replacement Information
      Description
      OverviewA panel containing 16 potent, selective and cell-permeable inhibitors that is useful for the study of TLR signaling: 1 mg of TIRAP Inhibitor Peptide, Cell-Permeable (Cat. No. 613570), 10 mg of IL-1R Antagonist (Cat. No. 407616), 5 mg of Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor (Cat. No. 407601), 1 mg of (5Z)-7-Oxozeaenol, Curvularia sp. (Cat. No. 499610), 10 mg of BX-795 (Cat. No. 204001), 5 mg of NBD-Binding Peptide II, Cell Permeable, CTP-NBD (Cat. No. 480026), 25 mg of Cdc42/Rac1 GTPase Inhibitor, ML141 (Cat. No. 217708), 5 mg of PKR Inhibitor (Cat. No. 527450), 5 mg of LY294002 (Cat. No. 440202), 5 mg of U0126 (Cat. No. 662005), 1 mg of IKK Inhibitor VII (Cat. No. 401486), 10 mg of BAY 11-7082 (Cat. No. 196870), 1 mg of SB 203580 (Cat. No. 559389), 5 mg of SP600125 (Cat. No. 420119), 10 mg of STAT3 Inhibitor III, WP1066 (Cat. No. 573097), and 10 mg of MG-132 (Cat. No. 474787). Also provided with 15 ml of anhydrous DMSO (Cat. No. KP31817).
      Catalogue Number500528
      Brand Family Calbiochem®
      References
      ReferencesAksoy, E., et al. 2012. Nat. Immunol. 13, 1045.
      Kondo, T., et al. 2012. Trends Immunol. 33, 449.
      Kawai, T. and Akira, S., 2010. Nat. Immunol. 11, 373.
      Kong, L. and Ge, B.X., 2008. Cell Res. 18, 745.
      Gilliet, M., et al. 2008. Nat. Rev. Immunol. 8, 594.
      Verstrepen, L., et al. 2008. Cell. Mol. Life Sci. 65, 2964.
      Wong, C.K., et al. 2007. Am. J. Respir. Cell Mol. Biol. 37, 85.
      Kawai, T. and Akira, S., 2007. Trends Mol. Med. 13, 460.
      Product Information
      FormSolid
      Hygroscopic Hygroscopic
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetMajor hubs involved in TLR signaling cascade
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 36/38

      Irritating to eyes and skin.
      S PhraseS: 26-36-45

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Irritant
      Storage -20°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) each inhibitor. Each inhibitor solution is stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Identification Number
      Catalog Number GTIN
      500528

      Documentation

      InhibitorSelect™ TLR Signaling Pathway Panel - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Aksoy, E., et al. 2012. Nat. Immunol. 13, 1045.
      Kondo, T., et al. 2012. Trends Immunol. 33, 449.
      Kawai, T. and Akira, S., 2010. Nat. Immunol. 11, 373.
      Kong, L. and Ge, B.X., 2008. Cell Res. 18, 745.
      Gilliet, M., et al. 2008. Nat. Rev. Immunol. 8, 594.
      Verstrepen, L., et al. 2008. Cell. Mol. Life Sci. 65, 2964.
      Wong, C.K., et al. 2007. Am. J. Respir. Cell Mol. Biol. 37, 85.
      Kawai, T. and Akira, S., 2007. Trends Mol. Med. 13, 460.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision23-July-2013 JSW
      DescriptionA panel containing 16 potent, selective and cell-permeable inhibitors that is useful for the study of TLR signaling. This panel contains the following inhibitors and 15 ml anhydrous DMSO for reconstitution:
      FormSolid
      Intert gas (Yes/No) Packaged under inert gas
      SolubilityDMSO (supplied). Please refer to information provided on the CD for reconstitution information of individual inhibitors.
      Storage Protect from light
      -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) each inhibitor. Each inhibitor solution is stable for up to 3 months at -20°C.
      Toxicity Irritant
      ReferencesAksoy, E., et al. 2012. Nat. Immunol. 13, 1045.
      Kondo, T., et al. 2012. Trends Immunol. 33, 449.
      Kawai, T. and Akira, S., 2010. Nat. Immunol. 11, 373.
      Kong, L. and Ge, B.X., 2008. Cell Res. 18, 745.
      Gilliet, M., et al. 2008. Nat. Rev. Immunol. 8, 594.
      Verstrepen, L., et al. 2008. Cell. Mol. Life Sci. 65, 2964.
      Wong, C.K., et al. 2007. Am. J. Respir. Cell Mol. Biol. 37, 85.
      Kawai, T. and Akira, S., 2007. Trends Mol. Med. 13, 460.