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616466 InhibitorSelect™ TGF-βR and BMPR Signaling Pathway Inhibitor Panel

616466
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616466-1EA
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      Description
      OverviewA panel containing 18 potent, selective and cell-permeable inhibitors that are useful for the study of TGF-βR and BMPR signaling pathway: 2 mg of Akt Inhibitor XIII, Isozyme-Selective, Akti2-1/2 (Cat. No. 124030), 1 mg of Dorsomorphin (AMPK Inhibitor, Compound C; Cat. No. 171260), 5 mg of ET-18-OCH3 (Cat. No. 341207), 5 mg of IRAK-1/4 Inhibitor (Cat. No. 407601), 500 µg of JAK Inhibitor I, Pyridone 6 (Cat. No. 420099), 5 mg of MG-132 (Cat. No. 474790), 1 mg of (5Z)-7-Oxozeaenol, Curvularia sp. (Cat. No. 499610), 5 mg of p21-Activated Kinase Inhibitor III, IPA-3 (Cat. No. 506106), 1 mg of PD 169316 (Cat. No. 513030), 1 mg of PI-103 (Cat. No. 528100), 5 mg of Rac1 Inhibitor (Cat. No. 553502), 500 µg of Ro-31-8220 (Cat. No. 557520), 1 mg of Smad3 Inhibitor, SIS3 (Cat. No. 566405), 10 mg of STAT3 Inhibitor III, WP1066 (Cat. No. 573097), 1 mg of TGF-β RI Kinase Inhibitor II (Cat. No. 616452), 5 mg of TGF-β RI Kinase Inhibitor VI, SB431542 (Cat. No. 616461), 1 mg of U0126 (Cat. No. 662005), 1 mg of Y-27632 (Cat. No. 688000). Also provided with 15 ml of anhydrous DMSO (Cat. No. KP31817). Supplied with a data sheet.
      Catalogue Number616466
      Brand Family Calbiochem®
      Application Data

      References
      ReferencesPardali, E., et al. 2010. Trends Cell Biol. 20, 556.
      Mosse, Y.P., et al. 2009. Clin. Cancer Res. 15, 5609.
      Clarke, D.C. and Liu, X., 2008 Trends Cell Biol. 18, 430.
      Product Information
      FormSolid
      Hygroscopic Hygroscopic
      Quality LevelMQ100
      Applications
      Biological Information
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped with Blue Ice or with Dry Ice
      Toxicity Regulatory Review
      Storage -20°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) each inhibitor. Each inhibitor solution is stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      InhibitorSelect™ TGF-βR and BMPR Signaling Pathway Inhibitor Panel Certificates of Analysis

      TitleLot Number
      616466

      References

      Reference overview
      Pardali, E., et al. 2010. Trends Cell Biol. 20, 556.
      Mosse, Y.P., et al. 2009. Clin. Cancer Res. 15, 5609.
      Clarke, D.C. and Liu, X., 2008 Trends Cell Biol. 18, 430.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision21-July-2011 RFH
      Application Data

      DescriptionA panel containing 18 potent, selective and cell-permeable inhibitors that is useful for the study of TGF-βR and BMPR signaling pathway. This panel contains the following inhibitors as well as 15 ml anhydrous DMSO for reconstitution:
      FormSolid
      Intert gas (Yes/No) Packaged under inert gas
      SolubilityDMSO (supplied). Please refer to information provided on the CD for reconstitution information of individual inhibitors.
      Storage -20°C
      Hygroscopic
      Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) each inhibitor. Each inhibitor solution is stable for up to 3 months at -20°C.
      Toxicity Regulatory Review
      ReferencesPardali, E., et al. 2010. Trends Cell Biol. 20, 556.
      Mosse, Y.P., et al. 2009. Clin. Cancer Res. 15, 5609.
      Clarke, D.C. and Liu, X., 2008 Trends Cell Biol. 18, 430.